ATS 2019 Virtual Final Program

608 Context-Specific Maturation of Lung Progenitors Is Directed by Lung Matrices and Vascular Cell-Derived Extracellular Vesicles/ M. Ho, M. Ho, K.R. Chaudhary, D.J. Stewart, Ottawa, Canada, p.A2551 609 Development of Hydrogel Bioinks and 3D Bioprinting Techniques to Support Extended 3D Lung Tissue Culture In Vitro/ K.E. Bailey, N.J. Darling, D. Velu, T.J. D’Ovidio, M.L. Floren, S.R. Lammers, K.R. Stenmark, C.M. Magin, Aurora, CO, p.A2552 610 Lung Derived ECM/Polymer Composite Substrates to Investigate Composition and Stiffness-Dependent Cell-ECM Interactions/ R.A. Pouliot, A. Bhattacharyya, J.J. Uriarte, K. Xia, D.J. Weiss, Burlington, VT, p.A2553 611 Wnt/Planar Cell Polarity Pathway Signaling Between Endothelial Cell and Pericyte-Like Smooth Muscle Cells Enhance Vascular Repaving in an Acellular Lung Scaffold/ M. Ho, K.R. Chaudhary, D.J. Stewart, Ottawa, Canada, p.A2554 612 Human Lung Extracellular Matrix Hydrogels Replicate Biomechanics of Diseased and Nondiseased Lung/ R.H.J. de Hilster, M.R. Jonker, P.K. Sharma, M.N. Hylkema, M.C. Harmsen, J.K. Burgess, Groningen, Netherlands, p.A2555 613 A Novel Airway Cell Spray Device for In-Vivo Application of Cells/ S. Skolasinski, D. Osarfo-Akoto, V. Ranjendran, C. Meyer, Z. Syedain, A. Naqwi, A. Panoskaltsis-Mortari, Minneapolis, MN, p.A2556 614 Nanomechanical Assessment of Decellularized COPD Lung Scaffolds/ J.J. Uriarte, F.E. Uhl, R.A. Pouliot, S.A.M. Bou Jawde, S. Rolandsson Enes, B. Suki, D.J. Weiss, Burlington, VT, p.A2557 615 Recellularization of Decellularized Mouse Lung Airways Using Negative Pressure Directed Cell Delivery/ M. Ahmadipour, F. Gava Aoki, G. Karoubi, T. Waddell, Toronto, Canada, p.A2558 616 Matrix Stiffness Regulates NADPH Oxidase 4 by Post-Transcriptional Mechanisms/ G.B. Pereira, K.G. Dsouza, Y. Zhou, A. Venado, V.J. Thannickal, Birmingham, AL, p.A2559 617 Assessment of Myofibroblast Phenotype with Cellular Stretch on Substrates of Different Stiffness/ M. Thomas Freeberg, T.H. Thatcher, P.J. Sime, Rochester, NY, p.A2560 618 a-TAT1 Promotes Myofibroblast Activation and Lung Fibrosis Via Microtubule-Dependent Mechanotransduction Pathways/ A. Santos, Boston, MA, p.A2561 619 Type I Collagen-Targeted PET Imaging in Idiopathic Pulmonary Fibrosis: First-in-Human Studies/ S.B. Montesi, D. Izquierdo-Garcia, E.D. Abston, P. Desogere, S. Digumarthy, R. Seethamraju, M. Lanuti, C. Catana, P. Caravan, Boston, MA, p.A7349 BASIC • CLINICAL • TRANSLATIONAL POSTER DISCUSSION SESSION A108 PATHOPHYSIOLOGY IN DIFFUSE PARENCHYMAL LUNG DISEASES 2:15 p.m. - 4:15 p.m. KBHCCD Ballroom D Four (Level 3) Poster Viewing 2:15-3:00 Discussion 3:00-4:15 Chairing: D.J. Tschumperlin, PhD, Rochester, MN K. Ask, PhD, Hamilton, Canada M. Bhattacharya, MD, San Francisco, CA 701 Quantitative Computed Tomography in Systemic Sclerosis-Associated Interstitial Lung Disease: A Densitometric Assessment of Disease Severity/ D. Castillo Saldana, H.O. Coxson, C.J. Hague, D. Murphy, M. Kirby, J. Tschirren, J.P. Sieren, J.D. Newell, C.J. Ryerson, Vancouver, Canada, p.A2562 702 Quantitative Multi-Resolution Computed Tomography Measures of Lung Parenchyma and Airway Morphometry in Patients with Interstitial Lung Disease/ K. Ikezoe, D.M. Vasilescu, C.J. Hague, N. Tanabe, F. Xu, H.O. Coxson, J.C. Hogg, Vancouver, Canada, p.A2563 703 Quantitative Lung Function Imaging for Detection of Parenchymal Lung Abnormalities Using Four Dimensional Computed Tomography Scan/ G. Nair, N. Myzuik, T. Guerrero, S. Al-katib, D. Turner-Lawrence, E. Castillo, Royal Oak, MI, p.A2564 704 Identification of Expiratory Air Trapping in Thoracic Computed Tomography Using Deep Learning/ S. Ram, L. Reynolds, A.B. Fortuna, S. Galban, D.R. Vummidi, E.A. Kazerooni, M.K. Han, C.J. Galban, C. Hatt, Ann Arbor, MI, p.A2565 705 Pulmonary Function Tests and CT Scan Patterns in Patients with Pulmonary Sarcoidosis: Is There an Association?/ A.M. Lopes, J. Almeida, T. Sá, I. Moreira, S. Rosário, C. Rocha, R.D. Coelho, A. Borba, J.A. Cardoso, Lisboa, Portugal, p.A2566 706 Comparison of Hyperpolarized 3He and 129Xe MR Imaging in Patients with Cystic Fibrosis/ M.F. Koch, J.P. Mugler, J.F. Mata, K. Qing, N.J. Tustison, T.A. Altes, R.P. Thomen, Columbia, MO, p.A2567 707 Hyperpolarized 129Xe Diffusion MRI in Cystic Fibrosis Lung Disease: Evidence for Pathological Alveolar Enlargement/ Z.I. Cleveland, A.S. Bdaiwi, M.M. Hossain, L.L. Walkup, R.P. Thomen, K. Ruppert, H. Wang, M. Willmering, J.P. Clancy, J.C. Woods, Cincinnati, OH, p.A2568 708 Development and Testing of a Formula for Predicting Emphysema Extent in Patients with Idiopathic Pulmonary Fibrosis/ A.U. Wells, J. Jacob, G. Cross, J. Barnett, D. Weycker, M. Atwood, K.-U. Kirchgaessler, V. Cottin, London, United Kingdom, p.A2569 709 Evaluation of Airflow Obstruction by Spirometry in Adults with Cystic Fibrosis: Prevalence and Characteristics in a Large Care Center/ J.J. Tolle, Nashville, TN, p.A2570 710 Tidal Changes in Respiratory Resistance in Children with Cystic Fibrosis/ B. Kinghorn, M. Rosenfeld, S. McNamara, A. Genatossio, E. Sullivan, S.D. Davis, C. Clem, M. Davis, P.D. Sly, Z. Hantos, Seattle, WA, p.A2571 711 Distinct Amino Acids Help to Rectify Dysfunctional Epithelial Chloride and Sodium Transport in Primary Human Bronchial Epithelial Cells with CFTRdF508 Mutation/ X. Xu, T. Bui, A. Grosche, R.J. Bridges, S. Lin, S. Prabhakaran, M.N. Abu-Hasan, S. Vidyasagar, Gainesville, FL, p.A2572 ATS 2019 • Dallas, TX SUNDAY • MAY 19 115 SUNDAY AFTERNOON