ATS 2019 Virtual Final Program

310 Vitamin D Deficiency Is Associated with Increased Risk of Pulmonary Nontuberculous Mycobacteria in Cystic Fibrosis/ W. Richter, Y. Sun, M.N. Santos, J.A. Nguyen, A. Sidhaye, K. Psoter, K.A. Cohen, M.T. Jennings, Baltimore, MD, p.A2533 311 Detection and Differentiation of Mycobacterium Avium Complex Species Using Proteomic Based Discovery/ N. Lapinel, A.H. Zea, L. Davis, J. Guidry, J. Ali, New Orleans, LA, p.A2534 312 A Comparison of Microbiologic and Molecular Measures of Bacterial Burden in Adults with Nontuberculous Mycobacterial Lung Disease/ M. Holt, A.R. Levin, E. Epperson, C.L. Daley, R. Davidson, Denver, CO, p.A2535 313 Minimum Inhibitory Concentration Distributions for Mycobacterium Avium Complex, a North American Perspective/ F.E. Roy, L.C. Strnad, S.A.R. Siegel, K.L. Winthrop, M.-C. Domingo, J. Longtin, L. James, Portland, OR, p.A2536 314 Clinical Characteristics and Outcomes of Patients Undergoing Anti-Mycobacterial Therapy versus No Anti- Mycobacterial Therapy for Mycobacterium Avium Complex Pulmonary Disease/ K. Pennington, P. Escalante, Rochester, MN, p.A2537 315 Lower Dose of Ethambutol Reduce Ocular Toxicity Without Compromising Efficacy for Pulmonary Mycobacterium Avium Complex Disease/ T. Ando, H. Kage, Y. Matsumoto, T. Nagase, Tokyo, Japan, p.A2538 316 Short-Course Treatment Regimen and Morphism Mapping for Pulmonary Mycobacterium Kansasii/ S. Kant, J.-Y. Wang, G. MAgombedze, M. Chapagain, H.L. Huang, J.G. Pasipanodya, D. Deshpande, S.K. Heysell, T. Gumbo, Dallas, TX, p.A2539 317 Treatment of Mycobacterium Avium Subsp Hominissus (MAH) Lung Infections in Mice with Intranasally Instilled Liposomal Ciprofloxacin in Combination with Clarithromycin and Ethambutol/ L. Bermudez, A. Palmer, J.D. Blanchard, I. Gonda, Corvallis, OR, p.A2540 318 NTM Module and QOL-Bronchiectasis: Responsivity of Patient-Reported Outcomes to Treatment in Patients with Pulmonary Nontuberculous Mycobacterial Disease/ E. Henkle, K.L. Winthrop, A.L. Quittner, Portland, OR, p.A2541 319 Longitudinal Validity and Prognostic Significance of the St George’s Respiratory Questionnaire in 269 Patients with Pulmonary Mycobacterium Avium Complex Disease/ T. Ogawa, T. Asakura, S. Suzuki, S. Okamori, T. Kusumoto, H. Namkoong, K. Yagi, H. Kamata, M. Ishii, T. Betsuyaku, N. Hasegawa, Shinjuku-ku, Tokyo, Japan, p.A2542 320 Longitudinal Change of Quality of Life in Patients with Non-Tuberculous Mycobacterial Pulmonary Disease/ N. Kwak, S.-A. Kim, S.M. Choi, J. Lee, C.-H. Lee, J.-J. Yim, Seoul, Korea, Republic of, p.A2543 321 Evaluation of the In Vitro Bactericidal Activity of Drugs Alone and in Combination Against Actively Growing and Nutrient-Starved Populations of Mycobacterium Abscessus/ N.C. Ammerman, J. Lee, A. Agarwal, E.L. Nuermberger, Baltimore, MD, p.A7347 322 Temporal Changes in Respiratory Morbidity and Multimorbidity with Associated Risk Factors in an Italian General Population Sample/ G. Viegi, S. Maio, S. Baldacci, S. Fasola, M. Simoni, A. Angino, S. La Grutta, V. Muggeo, Pisa, Italy, p.A7348 BASIC • TRANSLATIONAL RAPID: RAPID ABSTRACT POSTER DISCUSSION SESSION A107 ENGINEERED AND REMODELLED MATRIX COMPARTMENTS 2:15 p.m. - 4:15 p.m. KBHCCD Ballroom D Three (Level 3) Abstract Summaries 2:15-2:45 Viewing/Discussion 2:45-4:15 Chairing: D.J. Weiss, MD, PhD, ATSF, Burlington, VT C.M. Magin, PhD, Aurora, CO D.E. Wagner, PhD, Lund, Sweden 601 Development of a Protocol to Study Bronchial Smooth Muscle Cells Behavior on a Natural Biologic Bronchial Matrix/ S. Ben Hamouda, A. Vargas, R. Boivin, J.-P. Lavoie, St-Hyacinthe, Canada, p.A2544 602 Quantitative Proteomic Profiling of Extracellular Matrix and Collagen PostTRANSLATIONAL Modifications in an In Vitro Model of Lung Fibrosis/ C.A. Staab-Weijnitz, J. Merl-Pham, T. Basak, L. Knueppel, D. Ramanujam, M. Athanason, J. Behr, S. Engelhardt, O. Eickelberg, S. Hauck, R. Vanacore, Munich, Germany, p.A2545 603 FAK-Related Non-Kinase Modulates Matrix Remodeling, Fibroblast Mechanosensing, and Myofibroblast Survival/ P. Che, X.-K. Zhao, L. Yu, M.A. Olman, Q. Ding, Birmingham, AL, p.A2546 604 Conditional Deletion of the Fibrillar Adhesion Protein Tensin1 Attenuates Extracellular Matrix Deposition in a Murine Model of Pulmonary Fibrosis/ K. Bernau, J.P. Leet, E.M. Bruhn, N.K. Sandbo, Madison, WI, p.A2547 605 Role of PGE Synthase Expression by Asthmatic Bronchial Epithelial Cells in Regulating Lung Fibroblast Extracellular Matrix Expression and Fibroblast-to-Myofibroblast Transition/ S.R. Reeves, K.A. Barrow, L.M. Rich, M.P. White, J.S. Debley, Seattle, WA, p.A2548 606 Comparative Transcriptional Profiling of Lung Fibroblasts from Aged and Young Mice Following Lung Injury Reveals Signature of Sustained Pro-Fibrotic Activation/ G. Ligresti, J.A. Meridew, Q. Tan, N. Caporarello, W. Liu, A.J. Haak, M.K. Dehankar, Y.S. Prakash, D.J. Tschumperlin, Rochester, MN, p.A2549 607 Single Cell RNA Sequencing of Human Lung Explants Identifies the Cell-Specific Contributions of Extracellular Matrix-Related Gene Expression/ S. Poli De Frias, T. Adams, J.C. Schupp, S. Chu, N. Neumark, F. Ahangari, G. Waskho, B. Raby, N. Kaminski, I. Rosas, Boston, MA, p.A2550 ATS 2019 • Dallas, TX 114 SUNDAY • MAY 19