ATS 2019 Virtual Final Program

2:15 Update in Cystic Fibrosis Management M.E. Egan, MD, New Haven, CT 2:45 Update in the Management of Aerodigestive Problems in the Pulmonary Clinic E.B. Hysinger, MD, MS, Cincinnati, OH 3:15 Update in the Management of Sleep Disordered Breathing in Children I. Narang, BMed Sci, MBBCH, MD, Toronto, Canada 3:45 Update on PCD and Non-CF Bronchiectasis A.J. Shapiro, MD, Montreal, Canada This session and the International Conference are supported by educational grants from Insmed Incorporated, Vertex Pharmaceuticals, Inc. All CME sessions have been planned and implemented in accordance with the Essential Areas and Policies of the Accreditation Council for Continuing Medical Education (ACCME) and are free of the control of commercial interests. CLINICAL CLINICAL TOPICS IN PULMONARY MEDICINE CME Credits Available: 2 MOC Points Available: 2 A82 CYSTIC FIBROSIS: HETEROGENEITY IN A MONOGENIC DISEASE Assemblies on Clinical Problems; Pediatrics 2:15 p.m. - 4:15 p.m. KBHCCD Ballroom C One-Two (Level 2) Target Audience Providers of cystic fibrosis; those with cystic fibrosis research interests Objectives At the conclusion of this session, the participant will be able to: • identify modifiable and non-modifiable reasons for heterogeneity in CF disease severity, prognosis, and treatment-related outcomes; • gain new strategies to manage the care of women and minorities with cystic fibrosis and improve their quality of life; • integrate new treatment options in discussing current and future CFTR modulators with CF patients. Although the proximal cause of cystic fibrosis has been identified as autosomal recessive mutations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene, there is substantial heterogeneity in disease severity, the rate of health decline, and treatment-related outcomes. For lung function alone, twin studies have shown that 50% of the variability is due to non-CFTR genes, while the other 50% is due to environmental factors, emphasizing the need to address both sources. This session will look at the influence of socioeconomic status, geopoliticial environment, specific CFTR genotypes (and the availability of CFTR modulators), and gender on these outcomes. Chairing: M. Sala, MD, Chicago, IL J.L. Taylor-Cousar, MD, MSc, ATSF, Denver, CO M. Jain, MD, Chicago, IL 2:15 A Patient's Perspective J. Eisenmann, Durham, NC 2:20 Heterogeneity in Cystic Fibrosis: Introduction M. Sala, MD, Chicago, IL 2:35 Socioeconomic Factors in Cystic Fibrosis Management and Prognosis S.A. McColley, MD, Chicago, IL 2:55 The Influence of Gender in Cystic Fibrosis R. Jain, MD, MSci, Dallas, TX 3:15 Access in Cystic Fibrosis: Comparisons Between Nations S.Z. Nasr, MD, Ann Arbor, MI 3:35 CFTR Modulators and the Personalization of Cystic Fibrosis Therapy M. Jain, MD, Chicago, IL 3:55 International Differences in Cystic Fibrosis Outcomes A. Stephenson, MD, PhD, Toronto, Canada This session and the International Conference are supported by an educational grant from Vertex Pharmaceuticals, Inc. All CME sessions have been planned and implemented in accordance with the Essential Areas and Policies of the Accreditation Council for Continuing Medical Education (ACCME) and are free of the control of commercial interests. CLINICAL RAVINDRA RAJMANE, MD MEMORIAL SYMPOSIUM CME Credits Available: 2 A83 GREAT CASES: CLINICAL, RADIOLOGIC, AND PATHOLOGIC CORRELATIONS BY MASTER PHYSICIANS : New! The Great Cases booklet is only available via the conference website http://conference.thoracic.org/go/great-cases or mobile app. Attendees wishing to access the booklet should bring a smart phone, tablet or laptop to the session. Council of Chapter Representatives 2:15 p.m. - 4:15 p.m. KBHCCD Ballroom C Three-Four (Level 2) Target Audience Clinicians in the fields of pulmonary and critical care medicine, pediatric pulmonology, sleep medicine, thoracic surgery, and infectious disease Objectives At the conclusion of this session, the participant will be able to: • integrate the clinical presentation, radiologic and pathologic findings for 7 challenging cases; • understand the clinical reasoning used to determine differential diagnosis by master clinicians using a multidisciplinary approach; • describe the associated pathology and radiology of the cases. Learners will have the opportunity to observe master clinicians approach challenging clinical problems by working through 7 unknown cases selected from the abstract pool. Collaboration with a master radiologist reviewing the films and a master pathologist reviewing pathology slides will demonstrate the multidisciplinary approach to difficult cases. The audience will participate though interactive questions that are tallied electronically. Additional discussion by presenters and master panelists will enhance the educational experience. Chairing: J. Sunderram, MD, ATSF, New Brunswick, NJ A.C. Wang, MD, La Jolla, CA ATS 2019 • Dallas, TX SUNDAY • MAY 19 99 SUNDAY AFTERNOON