ATS 2020 Advance Program

3:50 Novel Methods for Early Diagnosis of Usual Interstitial Pneumonitis (UIP)/IPF L.P. Hariri, BS, MD, PhD, Boston, MA BEHAVIORAL • CLINICAL CRITICAL CARE TRACK B84 EARLY SEPSIS CARE AND THE HOUR ONE BUNDLE: WHY? WHEN? WHO? HOW? Assemblies on Critical Care; Behavioral and Health Services Research; Clinical Problems; Nursing; Pediatrics 2:15 p.m. - 4:15 p.m. Target Audience Clinicians and trainees from multiple disciplines and settings who care for sepsis patients; individuals involved in sepsis research, quality improvement, advocacy, policy, or antibiotic stewardship Objectives At the conclusion of this session, the participant will be able to: • apply data supporting early antibiotic and fluid treatment in sepsis, associated controversies, and potential adverse effects of efforts to speed treatment initiation. This objective will provide an evidence base for improved clinical practice. • identify barriers to prompt treatment for sepsis patients. This objective will help attendees improve care delivery for sepsis for patients at their institutions. • apply and adapt novel strategies to deliver high-quality sepsis care. This objective will help attendees find innovative methods to ensure high-quality care for sepsis patients. International guidelines and government mandates emphasize early treatment and especially early antibiotics for septic patients. In particular, observational studies show sepsis outcomes worsen for every hour effective antibiotics are delayed. Despite increasing evidence and biological plausibility, however, controversy persists regarding this central premise, measurement of treatment timing, and implementation of a one-hour target for antibiotic initiation specifically and sepsis treatment generally. This session will review the current evidence and controversies around early antibiotic and fluid treatment for sepsis, discuss potential adverse effects of prioritizing early treatment, and evaluate the barriers to rapid treatment initiation and potential methods to overcome them. Chairing: I.D. Peltan, MD, MSc, Murray, UT H.C. Prescott, MD, MSc, Ann Arbor, MI V.X. Liu, MD, MS, Oakland, CA 2:15 A Patient's Perspective Speaker To Be Announced 2:20 Rapid Antibiotics Saves Lives: Truth, Hype and Consequences H.C. Prescott, MD, MSc, Ann Arbor, MI 2:34 Early IV Fluids in Adult and Pediatric Sepsis: Too Much of a Good Thing? A.B. Maddux, MD, MSCR, Aurora, CO 2:48 Treatment Timing by Sepsis Subgroups: One Size Fits None? V.X. Liu, MD, MS, Oakland, CA 3:02 Sepsis Mandates: The View From Ground Zero T.M. Osborn, MD, MPH, Saint Louis, MO 3:16 Why Do We Struggle to Implement Rapid Treatment? I.D. Peltan, MD, MSc, Murray, UT 3:30 High-Quality Sepsis Care in Lower Resource Settings L.A. Gorordo Delsol, MD, Mexico City, Mexico 3:45 Can We Help Clinicians Make Better Decisions Faster? B.E. Jones, MD, MSc, Salt Lake City, UT 4:00 Interprofessional Teams, Sepsis, and the Science of Implementation D.K. Costa, PhD, RN, Ann Arbor, MI ATS 2020 • Philadelphia, PA MONDAY • MAY 18 89