ATS 2020 Advance Program

12:30 Insights About Immunobiology and Alveolar Physiology of the Aged Lung J. Bhattacharya, MD, New York, NY 12:36 NALCA: The Normal Aging Lung Cell Atlas N. Kaminski, MD, New Haven, CT 12:49 Age-Related Changes in Genome and Epigenome in Human Lung in Relation to Smoking S.D. Spivack, MD, MPH, Bronx, NY 1:02 The Human Distal Airway Aging Project R. Shaykhiev, MD, PhD, New York, NY DIVISION OF LUNG DISEASES/NHLBI L17 NEW FINDINGS FROM THE SUBPOPULATIONS AND INTERMEDIATE OUTCOME MEASURES IN COPD (SPIROMICS) STUDY 12:15 p.m. - 1:15 p.m. Target Audience Researchers, medical trainees, and those with an interest in COPD pathogenesis, Objectives At the conclusion of this session, the participant will be able to: • learn about imaging phenotyping of COPD; • understand and learn about molecular phenotyping of COPD; • learn about clinical phenotyping of COPD. SPIROMICS is an NHLBI-sponsored study that supports the prospective collection and analysis of phenotypic, biomarker, genetic, genomic, and clinical data from subjects with COPD for the purpose of identifying subpopulations and the biological underpinnings of clinical phenotypes in COPD. Participants in this session will learn about the progress in SPIROMICS including results and analyses of SPIROMICS data and plans for the SPIROMICS II follow-up study. Chairing: P. Woodruff, MD, MPH, San Francisco, CA L. Postow, PhD, Bethesda, MD 12:15 Introduction to SPIROMICS II P. Woodruff, MD, MPH, San Francisco, CA 12:19 A Cytokine Response Signature in Airway Epithelial Cells Identifies a COPD Patient Subgroup S. Christenson, MD, MS, San Francisco, CA 12:33 The Association of Allergic Disease with Clinical Outcomes in COPD N. Putcha, MD, Baltimore, MD 12:47 The SPIROMICS Heart Failure Study: Rediscovering Cardiopulmonary Interactions R.G. Barr, MD, DrPH, New York, NY 1:01 The Early COPD Cohort Study M.K. Han, MD, MS, Ann Arbor, MI DIVISION OF LUNG DISEASES/NHLBI L18 LESSONS LEARNED IN NHLBI ASTHMA EMPOWERMENT CLINICAL TRIALS: COMMUNITY AND SCHOOL ENGAGEMENT 12:15 p.m. - 1:15 p.m. Target Audience Researchers or asthma care providers interested in community based asthma interventions including schools. Objectives At the conclusion of this session, the participant will be able to: • understand the options for providing asthma care for children in schools; • improve the quality of asthma care for children by engaging school based resources; • recognize the interventions that can be performed by community health workers in asthma care. The session will provide a discussion of the lessons learned from the investigators conducting 4 ongoing clinical trials in the NHLBI funded Asthma ATS 2020 • Philadelphia, PA 82 MONDAY • MAY 18