ATS 2020 Advance Program

2:20 Transplant Evaluation and Post-Transplant Management A. Courtwright, MD, PhD, Philadelphia, PA 2:40 Panel Discussion CLINICAL • TRANSLATIONAL CRITICAL CARE TRACK D84 TWENTY YEARS INTO THE LOW TIDAL VOLUME ERA FOR ARDS: WHAT ELSE SHOULD WE BE DOING? Assemblies on Critical Care; Clinical Problems 1:00 p.m. - 3:00 p.m. Target Audience All practicing clinicians and trainees in critical care, clinical and translational researchers interested in acute respiratory distress syndrome (ARDS) and ventilator-induced lung injury (VILI). Objectives At the conclusion of this session, the participant will be able to: • understand the latest evidence regarding mechanical ventilation management for patients with ARDS beyond low tidal volume ventilation; • increased knowledge of the identification of patients who could benefit from personalized strategies beyond low tidal volume ventilation in ARDS and prevent further VILI; • recognize the limits of bedside VILI detection, including that the absence of tools for routine detection currently does not exclude the possibility of ongoing VILI risk. Low tidal volume ventilation is the standard of care for the management of ARDS to minimize ventilator-induced lung injury (VILI). The optimal approach to managing patients at highest risk for VILI remains uncertain. Numerous strategies have been proposed, including high PEEP, reduced respiratory drive, and apneic ventilation, despite conflicting scientific evidence. This dynamic session will explore, in a pro/con format, ongoing controversies in the management of ARDS, including open- versus closed-lung strategies, determining optimal respiratory effort, and the potential for translational biology to help identify patients at greatest risk of VILI for whom escalating lung-protective interventions may be most appropriate. Chairing: P. Madahar, MD, MS, New York, NY B.K. Patel, MD, Chicago, IL S. Sahetya, MD, MHS, Baltimore, MD E. Goligher, MD, Toronto, Canada 1:00 A Patient's Perspective Speaker To Be Announced 1:05 Breathe “Normally”: Targeting Normal Respiratory Effort to Protect the Diaphragm E. Goligher, MD, Toronto, Canada 1:14 Breathe “Easy”: Eliminating Respiratory Effort to Protect the Lungs D. Abrams, MD, New York, NY 1:23 Mind Over Body: Targeting Consciousness to Protect Against Over-Sedation B.K. Patel, MD, Chicago, IL 1:32 Audience Questions With Panel Discussion 1:41 Open or Closed? Open-Lung Strategies to Protect Against Atelectrauma M.B.P. Amato, MD, Sao Paulo, Brazil 1:50 Open or Closed? Closed-Lung Strategies to Protect Against Volutrauma S. Sahetya, MD, MHS, Baltimore, MD 2:00 Aiming for Apnea: Eliminating Breathing Altogether to Protect Against Atelectrauma and Volutrauma D. Brodie, MD, New York, NY 2:10 Audience Questions With Panel Discussion 2:20 Beyond the Bedside: Developing Markers of Biophysical Lung Injury to Protect Against Guessing N. Meyer, MD, MS, Philadelphia, PA 2:30 Abandoning ARDS: Admitting What We Don’t Know, so We Can Learn What We Should Do C.S. Calfee, MD, MAS, San Francisco, CA 2:40 Audience Questions With Panel Discussion ATS 2020 • Philadelphia, PA 142 WEDNESDAY • MAY 20