ATS 2020 Advance Program

10:19 An Integrated Role of Distal Epithelial Cell Membrane Repair in Lung Health X. Zhao, MB, PhD, Norfolk, VA 10:47 Effects of Aging and Injury on ATTI to ATI Transition Y. Liu, PhD, Chicago, IL 10:21 Asymmetric Activation of Mesenchyme Transcription Factors Disrupts Distal Alveoli Maintenance and Injury Responses T. Peng, MD, San Francisco, CA 10:39 Harnessing Hematopoietic-Vascular Niche to Promote Alveoli Repair After Sterile Injury B.-S. Ding, PhD, New York, NY 10:57 The Role of Myeloid and Lymphoid Cells in the Alveolar Niche Regeneration J.R. Rock, PhD, Boston, MA BEHAVIORAL • CLINICAL SCIENTIFIC SYMPOSIUM C8 IMPLEMENTATION SCIENCE IN THE ICU 2.0: BEYOND BARRIERS AND FACILITATORS Assemblies on Behavioral and Health Services Research; Clinical Problems; Critical Care; Nursing 9:15 a.m. - 11:15 a.m. Target Audience Multi-disciplinary researchers and inter-professional clinicians who seek to learn about the challenges and solutions to implementation of evidence-based practices in the ICU. Objectives At the conclusion of this session, the participant will be able to: • learn how to select and apply conceptual frameworks for different phases of implementation research; • understand and learn the importance of stakeholder engagement and be able to apply principles from behavioral economics and bioinformatics in a variety of ICU settings to close the evidence-to-practice gap; • learn about challenges of and solutions to funding implementation science research and implementation of complex interventions in the ICU. Implementation science involves the study of strategies to overcome evidence-to-practice gaps. Prior well-attended ATS sessions have discussed identification of barriers and facilitators to the adoption of ICU best practices, an important first step in bridging that gap. In this session, experts will build upon these concepts. Discussions will cover the selection and application of conceptual frameworks that enable the systematic development, management, and evaluation of interventions; innovative approaches to implementation and de-implementation strategies, including stakeholder engagement and the application of behavioral economics and bioinformatics; and challenges and solutions to the funding and execution of pragmatic clinical trials. Chairing: K.C. Vranas, MD, Portland, OR C.H. Weiss, MD, MS, Evanston, IL A.E. Sales, PhD, RN, Ann Arbor, MI 9:15 Closing the Evidence-to-Practice Gap: Selecting and Applying Implementation Science Frameworks in the ICU A.E. Sales, PhD, RN, Ann Arbor, MI 9:30 InnovativeMethods to IdentifyBarriers and Facilitators toEvidence-BasedPractices in the ICU C.H. Weiss, MD, MS, Evanston, IL 9:45 Connecting the Dots between Stakeholder Identification and Evidence Implementation: A Practical Guide D.K. Costa, PhD, RN, Ann Arbor, MI 10:00 Leveraging Bioinformatics Tools to Integrate ICU Clinical Practice Guidelines into Daily Practice V. Liu, MD, MS, Oakland, CA 10:15 Implementation of Complex Interventions to Improve Patient Safety in the ICU M. Lane-Fall, MD, MS, Philadelphia, PA 10:30 “Nudging” Toward Adherence to Evidence-Based Practices in the ICU M.P. Kerlin, MD, MS, Philadelphia, PA ATS 2020 • Philadelphia, PA TUESDAY • MAY 19 105