ATS 2019 Virtual Final Program

P242 Cognitive Function Is More Impaired in Chronic Obstructive Pulmonary Disease Patients with Skeletal Muscle Dysfunction and Is Associated with Disturbances in Tryptophan Metabolism/ C. Cruthirds, R.I. Harrykissoon, A.J. Zachria, N.E.P. Deutz, M.P.K.J. Engelen, College Station, TX, p.A2058 P243 The Mitochondrial Motility in Diaphragm and Quadriceps of COPD Rat Before and After Rehabilitation/ S. Qumu, Beijing, China, p.A2059 P244 Impaired Oxidative Phosphorylative Capacity in Skeletal Muscle of Patients Referred for Pulmonary Rehabilitation/ P.T. Diaz, S. Smart, B. McCarthy, J. Drake, S. Raman, Columbus, OH, p.A2060 P245 Acute Effect of Maximal Dynamic Exercise on Endothelial Function in COPD Patients/ F. Caruso, C.D.L. Goulart, G.M. Morao, G.P. Areas, L.C. Carvalho Jr, R.G. Mendes, A.B. Silva, Sao Carlos, Brazil, p.A2061 P246 Quadriceps Muscle Postactivation Potentiation and Twitch Contraction Time in Elderly Men with and Without COPD/ S. Chandiramani, G. Pellegrino, T. Schnell, G.F. Sferrazza Papa, E.G. Collins, M.J. Tobin, F. Laghi, Hines, IL, p.A2062 P247 Exercise Capacity May Be More Strongly Associated with Health Status in Alpha-1 Antitrypsin COPD Patients than in Alpha-1 Antitrypsin Replete COPD Patients/ E. Durkan, T. Carroll, N.M. Moyna, N.G. McElvaney, Dublin, Ireland, p.A2063 P248 Recovery of Muscle Strength and Endurance after Hospitalization in Patients with Medical Illness/ S. Baveja, B. Akpa, J. Ferris, J. Hecht, E. Heidel, R. Dhand, Knoxville, TN, p.A2064 P249 Subjective Assessment of Perceived Activity and Weakness Score (PAWS) Correlates with Objective Assessments of Muscle Strength and Endurance in Patients Admitted to a Hospital with Medical Illness/ S. Baveja, B. Akpa, J. Ferris, J. Hecht, E. Heidel, R. Dhand, Knoxville, TN, p.A2065 P250 Effects of Aerobic Training on Respiratory Mechanics and Lung Inflammation in Rats with Hepatopulmonary Syndrome/ C. Melo-Silva, W. Nunes, E.S.P. Nascimento, S. Silva, M. Roza, O. Nobrega, W. Silva, G. Avelar, V. Amado, Brasilia, Brazil, p.A2066 P251 Effects of Combined Exercise Training in Respiratory System Mechanical Properties and Inflammation in Rats with Hepatopulmonary Syndrome/ E. Nascimento, W. Nunes, S. Costa-Silva, M. Roza, O. Nobrega, W. Machado-Silva, V. Amado, C. Melo-Silva, Brasilia, Brazil, p.A2067 P252 Relation of Subjective Assessment of Perceived Activity and Weakness Score (PAWS) to Health Outcomes Up to 90 Days After Hospital Admission for a Medical Illness/ B. Akpa, S. Baveja, J. Ferris, J. Hecht, E. Heidel, R. Dhand, Knoxville, TN, p.A2068 BASIC • TRANSLATIONAL THEMATIC POSTER SESSION A60 LUNG INJURY, SEPSIS, AND ARDS 9:15 a.m. - 4:15 p.m. KBHCCD Area C (Hall F, Level 2) Viewing: Posters will be on display for entire session. Discussion: 11:15-12:00: authors will be present for individual discussion 12:00-1:00: authors will be present for discussion with assigned facilitators. Facilitator : B.D. Southern, MD, Cleveland, OH P254 An Imaging Approach to Assess the Impact of Systemic Hypoxia on Pulmonary Lactate Production: A Hyperpolarized Carbon-13 Study/ M. Pourfathi, M. Cereda, Y. Xin, S. Kdlecek, H. Hamedani, I. Duncan, S. Siddiqui, H. Profka, K. Ruppert, L. Loza, F. Amzajerdian, R. Baron, T. Achekzai, F. Sertic, F. Bermudez, R.R. Rizi, Philadelphia, PA, p.A2069 P255 Visualizing Local Lactate Production in Injured Lungs Using Hyperpolarized Carbon-13 MRI/ M. Pourfathi, Y. Xin, S. Kdlecek, M. Cereda, H. Hamedani, I. Duncan, S. Siddiqui, H. Profka, K. Ruppert, L. Loza, F. Amzajerdian, R. Baron, T. Achekzai, F. Sertic, F. Bermudez, R.R. Rizi, Philadelphia, PA, p.A2070 P256 Role of Antigen Processing and Presentation Pathway in Sepsis/ L. Gao, E.Y.L. Liu, Baltimore, MD, p.A2071 P257 Gram Negative Infection Accelerates Lung Endothelial Cell Death Through Regulation of MicroRNA-1/Angiopoietin-2 Pathway/ A. Korde, S. Anderson, M. Haslip, S. Takyar, New Haven, CT, p.A2072 P258 In Vitro Comparison of the Immunomodulatory Effects of Sevoflurane and Propofol in a Sepsis Model/ T. Oliveira, C.L. Braga, P.L. Silva, P.R.M. Rocco, F.F. Cruz, Rio de Janeiro, Brazil, p.A2073 P259 Mesenchymal Stromal Cell Effects on the Innate and Adaptive Immune Response to Sepsis/ S. Horie, J. Brady, C. Masterson, H. González, D. Byrnes, D. O’Toole, J.G. Laffey, Galway, Ireland, p.A2074 P260 Anti-Aging Protein Klotho Modulates the Neutrophil Response to Mediators of Sepsis/ C. Molina, P.G. Arndt, Minneapolis, MN, p.A2075 P261 LL-37 and Its Analog FF/CAP18 Attenuated Neutrophil Migration in Sepsis-Induced Acute Lung Injury/ W. Zhang, L. Huang, Y. Huang, G. Zhu, Beijing, China, p.A2076 P262 Identification of the IL-1ß Producing Cell Type in the Lung Through Primary Cell Expression Profiling in Intact Lung Tissue/ A. Prakash, X. Tian, Q. Liu, San Francisco, CA, p.A2077 P263 Pulmonary Challenge Induces Age-Dependent Changes in Pancreatic Activity/ E.J. Miller, K. Ochani, K. Lin, P. Wang, S.F. Liu, H.L.R. Rilo, Manhasset, NY, p.A2078 ATS 2019 • Dallas, TX 78 SUNDAY • MAY 19