ATS 2019 Virtual Final Program

904 Risk Factors and Protective Factors for Recurrent Wheezing in the First Year of Life in the City of Cordoba, Argentina/ A. Teijeiro, M.N. Cuello, M.G. Raiden, R.E. Vieyra, Cordoba, Argentina, p.A1184 905 Correlation Between Bronchiolitis Severity and Respiratory Syncytial Virus Genotype During Fourteen Epidemic Seasons/ G. Di Mattia, A. Frassanito, L. Petrarca, R. Nenna, M. Di Martino, S. Persia, D. La Regina, C. Scagnolari, A. Pierangeli, F. Midulla, Rome, Italy, p.A1185 906 Burden and Risk Factors for Severe Human Metapneumovirus Disease in Children from a Developing Country Setting/ I. Esteban, R. Libster, S. Coviello, E. Bergel, F.P. Polack, Buenos Aires, Argentina, p.A1186 907 Clinical Manifestations of Parainfluenza Virus Type 4 in Hospitalized Children in South Korea: A Large-Scale and Comparative Study to Parainfluenza Types 1-3/ Y. Sun, Incheon, Korea, Republic of, p.A1187 908 Identification of Newborn Screening Metabolites and Associated Risk of Infant Bronchiolitis/ B. Donovan, K.N. Turi, T. Gebretsadik, S.L. Havstad, J.E. Gern, D.J. Jackson, C. Ober, S.V. Lynch, C.M. Seroogy, E.M. Zoratti, T.V. Hartert, Nashville, TN, p.A1188 909 Gut Microbiome Components and Wheeze in 2-Year-Old Children/ J. Zhang, W. Liu, Y. Xing, C. Hu, Y. Li, W. Xia, K.E. Pinkerton, S. Xu, Hubei, China, p.A1189 910 HIV Infection Is Independently Associated with Impaired FEV1 Among Adolescents in Nairobi/ L. Ellington, E. Maleche-Obimbo, M. Rosenfeld, T.E. West, C.J. McGrath, J. Lukorito, C. Njiru, A. Cagle, J.S. Zifodya, S. Eskander, M.H. Chung, K. Crothers, E.F. Attia, Seattle, WA, p.A1190 911 Human Metapneumovirus Among Young Children with Severe Pneumonia in Africa and Asia: Findings from the Pneumonia Etiology Research for Child Health (PERCH) Case-Control Study/ R. Miyakawa, M. Knoll, Baltimore, MD, p.A1191 912 Prevalence of Hypoxemia amongst Children with Pneumonia in Secondary Health Facilities in Nigeria/ A.O. Alohan, A.A. Bakare, A.I. Ayede, A.G. Falade, Ibadan, Nigeria, p.A1192 913 New Clinical Insights into Potentially Modifiable Risk Factors for Childhood Pneumonia in Developing Countries: Implications for Clinical Practice and Policy/ N.K. Bhatta, S. Yadav, L.R. Sah, R.R. Singh, Dharan, Nepal, p.A1193 914 Prophylactic Use of Macrolides During Winter for Children with Chronic Lung Disease: A Double-Blind Randomized Controlled Trial/ H. Emanuel, A. Yadav, G.N. Colasurdo, J.M. Stark, C.K. Jon, K. McBeth, T. Gonzales, T.S. Harris, C. Bell, S.S. Hashmi, E. Avritscher, J.E. Tyson, C. Pedroza, R.A. Mosquera, Houston, TX, p.A1194 915 Platelet Activation as an Early Biomarker for Prediction of Bacteremia in Emergency Department Pediatric Patients/ L. Jankauskaite, E. Tamelyte, G. Vaicekauskiene, T. Lapinskas, Kaunas, Lithuania, p.A1195 916 Acute Smoke Exposure Significantly Increases Bacterial Burden of Haemophilus Influenzae in Murine Model of Early Life Smoke Exposure/ B.C. Hunt, X. Xu, J. Li, L. Viera, J. Blackburn, E. Blalock, A. Gaggar, W.E. Swords, Birmingham, AL, p.A1196 917 Bacterial Pneumonia Predicts Ongoing Chronic Pulmonary Dysfunction in Previously Healthy Infants/ G. Keim, N. Yehya, D. Spear, M.W. Hall, L. Loftis, J. Alten, J. McArthur, P.P. Patwari, R.J. Freishtat, D. Willson, J. Straumanis, N. Thomas, Philadelphia, PA, p.A1197 918 Interventions and Timing of Death in Critically Ill Children Admitted with Infections to North American PICUs: Analysis of 100,472 Admissions from 2009-2014/ K. Johnson, M. Görges, S. Murthy, Vancouver, Canada, p.A1198 919 Utilization of Procalcitonin as a Diagnostic Biomarker of Pediatric Ventilator-Associated Pneumonia in Patients with Congenital Heart Disease Following Cardiac Surgery/ F.J.L. Dago-oc, Quezon City, Philippines, p.A1199 920 Temporal Changes in the Lower Airway Microbiome Are Associated with Development of Ventilator Associated Pneumonia in Mechanically Ventilated Children/ P.M. Mourani, M. Sontag, B. Wagner, K. Williamson, J.K. Harris, R. Reeder, C. Locandro, T.C. Carpenter, A.B. Maddux, K. Ziegler, E. Simoes, C.M. Osborne, C. Langelier, K. Kalantar, J. Kamm, M.W. Hall, A. Zuppa, J. Carcillo, K. Meert, A. Sapru, M. Pollack, P. McQuillen, R. Tamburro, J.M. Dean, Aurora, CO, p.A1200 921 Exposure to RSV in Late Pregnancy Increases RSV-Induced Cord Blood IFN- g and Decreases Risk of Subsequent RSV-LRIs/ R. Nenna, D.A. Stern, A. Spangenberg, T.F. Carr, A.L. Wright, F.D. Martinez, M.J. Halonen, Tucson, AZ, p.A7299 BASIC • TRANSLATIONAL RAPID: RAPID ABSTRACT POSTER DISCUSSION SESSION A28 BACTERIAL AND VIRAL LUNG INFECTIONS AND PATHOGENESIS 9:15 a.m. - 11:15 a.m. KBHCCD Ballroom A Four (Level 2) Abstract Summaries 9:15-9:45 Viewing/Discussion 9:45-11:15 Chairing: A.E. Samarasinghe, PhD, Memphis, TN J.P. Mizgerd, ScD, ATSF, Boston, MA C. Steele, PhD, New Orleans, LA 301 Effects of Cigarette Smoke Condensate (CSC) on Clarithromycin-Mediated Alterations in Resistance Gene Expression by Streptococcus Pneumoniae/ C. Feldman, G. Matapa, T. Dix-Peek, R. Cockeran, R. Anderson, H. Steel, Johannesburg, South Africa, p.A1201 302 Inducible Epithelial Resistance Prevents CD8 + T Cell-Dependent Lethal Immunopathology Following Respiratory Viral Infections/ S. Wali, D. Goldblatt, J.R. Flores Gonzalez, M.J. Tuvim, B.F. Dickey, S.E. Evans, Houston, TX, p.A1202 303 NLRP12 Negatively Regulates Pulmonary Host Defense in Gram-Positive Bacterial Pneumonia/ L. Ghimire, S. Paudel, S. Jeyaseelan, Baton Rouge, LA, p.A1203 ATS 2019 • Dallas, TX SUNDAY • MAY 19 41 SUNDAY MORNING