ATS 2019 Virtual Final Program

702 Observing Alveolar Collapse in Unilateral Acute Lung Injury in a Rabbit Model Using 1D Real-Time Hyperpolarized Xenon-129 MRI/ K. Ruppert, Y. Xin, F. Amzajerdian, H. Hamedani, T. Achekzai, R. Baron, I. Duncan, H. Profka, S. Siddiqui, M. Pourfathi, F. Sertic, M. Cereda, S. Kadlecek, R.R. Rizi, Philadelphia, PA, p.A7239 703 The Effect of Post Injury Exercise Intensity on Muscle Proteolysis and Metabolism in Lung Injured Mice/ L. Belfield, C. Liu, K. Gibbs, R.D. Stapleton, B.T. Suratt, M.J. Toth, D.C. Files, Winston-Salem, NC, p.A7240 704 Alignment of Intercellular Stress Affects Endothelial Barrier Function/ C.C. Hardin, T. Nguyen, Boston, MA, p.A7241 705 TSG-6 Secreted from Human Umbilical Cord-Derived Mesenchymal Stem Cells Attenuate Severe Burn-Induced Acute Lung Injury Via Inhibiting Inflammatory Reactions/ X. Hu, L. Liu, Y. Wang, Y. Yu, Y. Liu, J. Chai, Beijing, China, p.A7242 706 Stretch and Mechanical Ventilator-Induced Senescence in Experimental Lung Injury/ R.L. Heise, M.S. Valentine, S. Chindal, A. Cordero, F.J. Kamga Gninzeko, Richmond, VA, p.A7243 707 Attenuation of Hyperoxic Lung Injury by Tracheal Delivery of Naturally Occurring Antisense Erythropoietin Receptor cDNA/ Y.-A. Zhang, K. Cao, C.C. Hsia, Dallas, TX, p.A7244 708 Mechanisms of Inflation-Induced ATP Release in Ex Vivo Rat Lungs: A Bioluminescence Imaging Study/ J.J. Tan, K. Furuya, F. Boudreault, E. Brochiero, R. Grygorczyk, Montreal, Canada, p.A7245 709 Multi-Frequency Oscillatory Ventilation Minimizes Spatial Gradients of Regional Strain Using 4D CT Image Registration in Porcine Lung Injury/ J. Herrmann, S.E. Gerard, W. Shao, J.M. Reinhardt, G.E. Christensen, E.A. Hoffman, M.L. Hawley, D.W. Kaczka, Iowa City, IA, p.A7246 710 Effects of Early Fluid Restriction in Mechanically Ventilated Lambs with ARDS/ S.A. Ingelse, M.M. IJland, L.M. van Loon, R.A. Bem, J.B.M. van Woensel, J. Lemson, Amsterdam, Netherlands, p.A7247 711 Radiologic Demonstration of the Synergistic Effect of PEEP and Prone Position in a Large Animal Model of Lung Injury/ T. Mandelbaum, Y. Xin, A. Lenart, K. Reutlinger, L. Thompson, S. Esposito, N. Abate, A. Kajanaku, P. Rangel, M. Del Signore, F. Sertic, F. Bermudez, M. Petrov, J.-P. Gottret, H. Profka, R.R. Rizi, B.P. Kavanagh, M. Cereda, Philadelphia, PA, p.A7248 712 Pairwise Registration Enhances Analysis of Lung Inflation in Prone vs. Supine Pigs with Lung Injury/ Y. Xin, M. Cereda, N. Tustison, S. Na, H. Hamedani, M. Pourfathi, S. Siddiqui, F. Amzajerdian, I. Duncan, L. Loza, T. Achekzai, F. Sertic, R. Baron, J. Ehrich, H. Profka, S. Kadlecek, J. Gee, B.P. Kavanagh, R.R. Rizi, Philadelphia, PA, p.A7249 713 Power of Ventilation and Its Relationship with Neutrophilic Inflammation in a Double Hit Model of Acute Respiratory Distress Syndrome/ R. Huhle, M. Scharffenberg, J.J.M. Wittenstein, M. Herzog, T. Kiss, T. Bluth, M. Gama de Abreu, Dresden, Germany, p.A7250 714 Sulforhodamine B Effect on Alveolar Surface Tension in Acute Respiratory Distress Syndrome Models/ T.L. Nguyen, C.E. Perlman, Hoboken, NJ, p.A7251 715 Effects of Dexamethasone and Docetaxel on Respiratory Mechanics and on Lung Morphology of Healthy Rats/ C. Melo-Silva, G. Scattolin, E. Gaio, M. Roza, V. Amado, Brasilia, Brazil, p.A7252 716 Host Immune Response in Pediatric Acute Respiratory Distress Syndrome/ T. Flerlage, E.K. Allen, A. Zamora, J. Crawford, P.G. Thomas, Memphis, TN, p.A7253 717 Regional Lung Perfusion and Tissue Density with Different Long Term Mechanical Ventilation Strategies and Endotoxemia Levels/ G.C. Motta Ribeiro, T. Winkler, M.R. Tucci, N. de Prost, S. Hashimoto, E.L.V. Costa, A.D.J. Santos, M.F. Vidal Melo, Rio de Janeiro, Brazil, p.A7254 718 NAMPT Is a Novel Participant and Therapeutic Target in Radiation-Induced Lung Injury (RILI)/ D.G. Valera, M. Valdez, K. Carrie, B. Sun, R.C. Oita, A.N. Garcia, A. Cress, L. Moreno-Vinasco, J.G.N. Garcia, Tucson, AZ, p.A7255 719 Effects of Acute Lung Inflammation on Zinc Pharmacokinetics/ D. Silva, H. Alsulimani, R.M. Baron, A. Arciniegas Rubio, R.M. Molina, J.D. Brain, Boston, MA, p.A7256 720 An Uncommon Cause of Drug Induced Lung Injury/ M. Bitar, F. Fuentes, D. Wiltse, Cincinnati, OH, p.A7257 721 Early ARDS Affects Regional Pulmonary Vascular Conductance in an Experimental Ovine Model/ A.D.J. Santos, N. De Prost, M. Tucci, G.C. Motta Ribeiro, T. Wellman, M.F. Vidal Melo, T. Winkler, Madrid, Spain, p.A7258 722 Lung Strain and Biological Response in Acute Pulmonary Edema/ L. Amado-Rodríguez, C. del Busto, I. Lopez-Alonso, C. Huidobro, D. Parra-Ruiz, M. Arias-Guillén, C. Morís, G.M. Albaiceta, Oviedo, Spain, p.A7481 CLINICAL RAPID: RAPID ABSTRACT POSTER DISCUSSION SESSION D109 SRN: OUTCOMES AND IMPACT OF SLEEP AND RESPIRATORY DISORDERS 1:30 p.m. - 3:30 p.m. OMNI DALLAS DOWNTOWN Trinity Ballroom 1-3 (Level 3) Abstract Summaries 1:30-2:00 Viewing/Discussion 2:00-3:30 Chairing: M. Kaminska, MD, Montreal, Canada C.M. Hoyos, BSc(Hons), MPH, PhD, Glebe, Australia R. Tamisier, MD, PhD, Grenoble, France 901 Shared Genetic Architecture Between Sleep and Blood Pressure Traits in Humans/ B.E. Cade, J. Lee, S.A. Gharib, D.J. Gottlieb, K.Y. He, D.R. Hillman, J. Liang, S. Mukherjee, L.J. Palmer, T. Sofer, H. Wang, A.V. Zinchuk, R. Saxena, S.M. Purcell, X. Zhu, S. Redline, Boston, MA, p.A7259 ATS 2019 • Dallas, TX WEDNESDAY • MAY 22 389 WEDNESDAY AFTERNOON

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