ATS 2019 Virtual Final Program

802 A Prospective, Randomized, Controlled Study of Inhaler Electronic Monitoring Devices to Improve Adherence in Children with Asthma/ T. Simoneau, Y. Sun, N. Gherlone, S. Almeida, M. Manice, J.P. Hollenbach, Hartford, CT, p.A7177 803 Breathing Counts: Addressing Barriers to Medication Use in High Risk Children with Asthma/ H. Hoch, M. Meier, J. Brinton, S.J. Szefler, Aurora, CO, p.A7178 804 Monitoring of the Respiratory Rate Recovery Time in Children with Asthma/ M.R. Kamp, B.J. Thio, F.H.C. de Jongh, J.M.M. Driessen, Enschede, Netherlands, p.A7179 805 The Utility of Flexible Bronchoscopy in Poorly-Controlled Asthma/ A. George, F. Ruangnapa, G. Lavins, K. McDowell, G. Huang, M.M. Hossain, T. Guilbert, Cincinnati, OH, p.A7180 806 Overweight and Obesity are Associated with Higher Tidal Volumes in Children with Asthma/ R.N. Shade, T.D. Wu, R.J. Koehl, H. Schneider, J. Kirkness, A. Bisant, R.S. Weber, D.H. Acciani, E. Brigham, N.N. Hansel, M.C. McCormack, Baltimore, MD, p.A7181 807 Objective Discharge Criteria Results in 48% Lower Readmission Rates for Children with Status Asthmaticus/ S.G. Bickel, R.L. Morton, A. Truman, A.R. O’Hagan, N.S. Eid, Louisville, KY, p.A7182 808 Predictors of Return Acute Asthma Visits Among Patients Receiving Guideline Recommended Discharge Management in the Emergency Department/ D. Radhakrishnan, C. Dhaliwal, T. Haji, G. Leung, S. Giangioppo, R. Surapaneni, Ottawa, Canada, p.A7183 809 Applying a Seasonal Asthma Exacerbation Predictive Index (saEPI) to an At-Risk Pediatric Population/ C. Shipp, G. Huang, M.M. Hossain, K.M. McDowell, Cincinnati, OH, p.A7184 810 Evaluation of Non-Invasive Nasal Immune Mediator Biomarkers of Asthma Control/ M.E. Rebuli, J.R. Hoffman, A.J. Burbank, M.L. Hernandez, I. Jaspers, Chapel Hill, NC, p.A7185 811 Utility of Salivary Cortisol in Corticotropin Releasing Hormone Test in Asthmatic Children/ Y. Murakami, C. Motomura, S. Honjo, H. Odajima, Fukuoka City, Japan, p.A7186 812 Eosinophil Phenotypes in Children with Asthma: Association with Asthma Control/ S. Shah, A.M. Fitzpatrick, S. Stephenson, M. Brown, Atlanta, GA, p.A7187 813 Low Levels of Bronchoalveolar Lavage Soluble Receptor for Advanced Glycation End Products Is Associated with Increased Serum Eosinophils and IgE Levels in Children with Asthma/ J.T. Patregnani, B.A. Brooks, E. Chorvinsky, D.K. Pillai, Washington, DC, p.A7188 814 Pharmacometabolomics of Bronchodilator Response in Asthma: Insights from the ADAPT Study/ R.S. Kelly, J. Sordillo, S.M. Lutz, L. Avila, M.E. Soto-Quiros, J.C. Celedon, M. McGeachie, A. Dahlin, K.G. Tantisira, S.T. Weiss, J.A. Lasky-Su, A.C. Wu, Boston, MA, p.A7189 815 Nasopharygeal Airway Microbiome in Children with Asthma and Resistant Airway Obstruction/ S. Panacherry, W. Huang, C.S. Bakshi, L.A. Parton, A.J. Dozor, S.S. Krishnan, Hawthorne, NY, p.A7190 816 Efficacy of As-Needed Budesonide/Formoterol for Reducing Severe Exacerbations in Adolescents with Mild Asthma: Pooled Subgroup Analysis of the SYGMA 1 and 2 Trials/ P. O’Byrne, E.D. Bateman, J.M. FitzGerald, P.J. Barnes, N. Zhong, V.K.T. Alagappan, S. Ivanov, G. Whelan, R. Lamarca, M. Puu, H.K. Reddel, Hamilton, Canada, p.A7191 817 The Long-Term Efficacy and Safety of Mepolizumab in Children from 6 to 11 Years of Age with Severe Eosinophilic Asthma/ J. Steinfeld, A. Gupta, M. Ikeda, B. Geng, J. Azmi, R. Price, E. Bradford, S. Yancey, Philadelphia, PA, p.A7192 818 PRKCH and Severe Asthma Exacerbations in Latino Children/ E. Forno, Q. Yan, E. Herrera-Luis, M. Pino-Yanes, R. Rios, Y.-Y. Han, S. Oh, E. Acosta-Perez, R. Zhang, D. Hu, C. Eng, S. Huntsman, L. Avila, N. Boutaoui, M.M. Cloutier, M.E. Soto-Quiros, S.T. Weiss, J.A. Lasky-Su, C.A. Figueiredo, M. Barreto, G. Canino, W. Chen, E.G. Burchard, J.C. Celedon, Pittsburgh, PA, P.A7478, p.A7478 819 Genetic Variation at the 17q21 Locus Is Associated with Altered Sphingolipids in Children/ J.G. Ono, T. Worgall, B.I. Kim, S. Worgall, New York, NY, p.A7479 BASIC • CLINICAL • TRANSLATIONAL POSTER DISCUSSION SESSION D106 PICK YOUR POISON: GENES, DRUGS, AND PAH 1:30 p.m. - 3:30 p.m. KBHCCD Ballroom A Four (Level 2) Poster Viewing 1:30-2:15 Discussion 2:15-3:30 Chairing: N.K. Dhillon, PhD, Kansas City, KS T. Lahm, MD, Indianapolis, IN M.R. Nicolls, MD, Palo Alto, CA 301 Orchestration of H3K27 Methylation Mechanisms of the Repression of MiR-124 and Therapeutic Implication in Pulmonary Hypertension/ H. Zhang, A. Laux, A. Flockton, D. Wang, C.-J. Hu, K.R. Stenmark, Aurora, CO, p.A7193 302 Evidence for Endothelial Barrier Dysfunction, Vascular Permeability and Altered Matrix Degradation in PAH Pathogenesis Using RNA-Sequence Analysis/ S. Mumby, V. Elyasigomari, C.K. Hui, F. Perros, A. Hautefort, M. Humbert, J. Wort, I.M. Adcock, London, United Kingdom, p.A7194 303 Long Non-Coding RNA Khps1 Promotes Pulmonary Arterial Smooth Muscle Cell Proliferation by Up-Regulating Sphingosine Kinase 1/ Y. Bai, A.D. Lockett, M. Teixeira Gomes, N.M. Jones, A. Carneiro, R.F. Machado, Shenyang, China, p.A7195 304 Integrated Analysis of Long Noncoding RNAs, mRNAs and Micro-RNAs from HIV-1 Protein and Cocaine Treated Human Pulmonary Arterial Smooth Muscle Cells/ M. Chinnappan, S. Gunewardena, N.K. Dhillon, Kansas City, KS, p.A7196 ATS 2019 • Dallas, TX 386 WEDNESDAY • MAY 22