ATS 2019 Virtual Final Program

P825 The Role of Cell Volume in Macrophage Polarization/ Y.-C. Chuang, K.-L. Huang, Taipei City, Taiwan, p.A6151 P826 Single Cell RNA Sequencing Identifies an Acute Respiratory Distress Syndrome Monocyte Response/ B.R. Rosborough, Y. Jiang, S. Rapport, B.J. McVerry, W. Chen, A. Ray, P. Ray, Pittsburgh, PA, p.A6152 P827 Surfactant Protein D Variants in Sepsis-Induced Lung Injury Following Ozone Exposure/ J.M. Radbel, K. Vayas, E. Abramova, O. Le-Hoang, V. Sunil, A. Gow, D.L. Laskin, New Brunswick, NJ, p.A6153 P828 The Role of IRAK-M in Regulating Innate Immune Responses Following Acute Ozone Exposure/ D. Herman, J.A. Englert, R.M. Tighe, R.V. Thomas Becket, H. Lee, M.D. Wewers, J.W. Christman, M.N. Ballinger, Columbus, OH, p.A6154 P829 Generation of C5aR1/C5aR2 Double Knockout Mice by CRISPR/Cas9 for Revealing Novel Aspects of Lung Injury/ M. Bosmann, M. Dudek, S. Walachowski, L. Eshkind, J.P. Mizgerd, Boston, MA, p.A7464 BASIC • CLINICAL • TRANSLATIONAL THEMATIC POSTER SESSION D33 PATHOLOGIC MECHANISMS IN PULMONARY INFECTIONS 9:15 a.m. - 3:30 p.m. KBHCCD Area B (Hall F, Level 2) Viewing: Posters will be on display for entire session. Discussion: 11:15-12:00: authors will be present for individual discussion 12:00-1:00: authors will be present for discussion with assigned facilitators. Facilitator : R.P. Dickson, MD, Ann Arbor, MI P133 Liver Activity Remodels the Lung Transcriptome and Limits Pneumonia Susceptibility During Sepsis/ C. Odom, Y. Kim, F.T. Korkmaz, E. Na, L. Baird, M.R. Jones, J.P. Mizgerd, K. Traber, L.J. Quinton, Boston, MA, p.A6155 P134 Eosinophilia Protects Against S. Aureus Systemic and Pneumonia Induced Bacteremia/ P. Krishack, T. Kuzel, T. Louviere, T. Decker, A.I. Sperling, P.A. Verhoef, Chicago, IL, p.A6156 P135 Lung CD4 + Resident Memory TRM Cells Remodel Epithelial Responses to Accelerate Neutrophil Recruitment/ A.T. Shenoy, G.A. Wasserman, E.I. Arafa, A.K. Wooten, N.M.S. Smith, I.M.C. Martin, E. Lipsitz, M.R. Jones, L.J. Quinton, J.P. Mizgerd, Boston, MA, p.A6157 P136 Metabolic Reprogramming Drives P. Aeruginosa Airway Infection/ K. Liimatta, S.A. Riquelme, C. Lozano, P.J. Planet, Y. Saenz, A.C. Uhlemann, A.S. Prince, New York, NY, p.A6158 P137 Anaphylatoxin C3a Enhances Recruitment of Monocytes Via Promoting the Production of Opsonins by Pleural Mesothelial Cells in Tuberculous Pleurisy/ W. Tang, X. Li, L. Luo, X. Hu, S. Deng, B. Zhao, C. Hu, J. Feng, Changsha, China, p.A6159 P138 Comparison of Pleural Effusion Features and Biomarkers Between Talaromycosis and Tuberculosis in Non-HIV-Infected Patients: A Prospective and Retrospective Study/ J. Zhang, Nanning, China, p.A6160 P139 Early Detection of Bordetella Pertussis and Bordetella Parapertussis Infection with Pertussis Antibody Ig-M, Ig-A, and IgM/IgA Ratio/ T. Matsuda, Misato-shi, Saitama, Japan, p.A6161 P140 Extracellular Matrix Protects Host from Escherichia Coli-Induced Respiratory Infection/ Y.P. Di, X. Zhang, L. Huleihel, N. Remlinger, T.W. Gilbert, Pittsburgh, PA, p.A6162 P141 Human Airway and Alveolar Resident Phagocytes Are Resistant to the Effects of Anthrax Lethal Toxin/ J.P. Metcalf, V.I. Patel, J.L. Booth, E. Duggan, Oklahoma City, OK, p.A6163 P142 HIV Infection Is Associated with a Loss of Ciliated Cells and an Increase of Secretory Cells Throughout the Airways/ Y. Strulovici-Barel, S. Ruparell, M. Pourabdollah Tootkaboni, V.K. Chirumamilla, A. Rogalski, M.R. Staudt, N.P.Y. Chung, K.M.F. Khan, S.L. O’Beirne, R.J. Kaner, R.G. Crystal, New York, NY, p.A6164 P143 Serum Soluble Interleukin-2 Receptor Is a Candidate Marker Differentiating Pneumocystis Jirovecii Pneumonia and Methotrexate-Induced Pneumonia in Patients with Rheumatoid Arthritis Under Methotrexate Therapy/ N. Sakamoto, S. Hara, H. Ishimoto, S. Nakashima, H. Yura, T. Miyamura, D. Okuno, A. Hara, T. Kakugawa, H. Kushima, H. Ishii, S. Noguchi, T. Kido, Y. Ishimatsu, K. Yatera, J. Kadota, H. Mukae, Nagasaki, Japan, p.A6165 Facilitator : A.K. Dickey, MD, Boston, MA P144 Determining Epithelial-Specific Roles for the Lung-Protective Cytokine Leukemia Inhibitory Factor (LIF) During Pneumonia/ E. Na, K.E. Traber, F.T. Korkmaz, Y. Kim, C.V. Odom, L.A. Baird, M.R. Jones, J.P. Mizgerd, L.J. Quinton, Boston, MA, p.A6166 P145 A Role for TLR2 in Pattern-Based Recognition of Virus Versus Non-Pathogen/ A. Rynda-Apple, K. Shepardson, L. Johns, K. Bertrand, B. Schwarz, T. Douglas, Bozeman, MT, p.A6167 P146 Long Noncoding RNA Regulates IRF1/IFNL Responses to Respiratory Viruses/ J. Yang, L. Kaphalia, W.J. Calhoun, A. Brasier, Galveston, TX, p.A6168 P147 The Identification of Rhinovirus C Susceptible Inbred Mice/ W.Y. Chan, I.M. Martin, K.P. Tao, T.T.J. Li, J.G.S. Tsun, W.W.Y. Yu, G.W.K. Wong, J.P. Mizgerd, Hong Kong, Hong Kong, p.A6169 P148 Simvastatin Inhibits Airway Epithelial H1N1 Influenza Viral Replication/ M.G. dela Pena-Ponce, N. Haigh, K. Chmiel, L.A. Miller, A.A. Zeki, Davis, CA, p.A6170 P149 Beta2 Adrenergic Receptor Proteolytic Cleavage in Response to RSV Infection in Human Primary Airway Smooth Muscle Cells/ T.J. Harford, S.V. Naga Prasad, F. Rezaee, G. Piedimonte, Cleveland, OH, p.A6171 P150 SPLUNC1 Enhances TLR3 Signaling in Mouse Lungs/ N. Schaefer, H.W. Chu, Denver, CO, p.A6172 P151 Soluble Tumor Necrosis Factor Receptor 1 Is a Potential Marker of Inflammation in the Trophoblast Associated with Cytomegalovirus Infection/ I.A. Andrievskaya, I.V. Dovzhikova, N.A. Ishutina, I.N. Gorikov, N.N. Dorofienko, K.K. Petrova, N.G. Prikhodko, Blagoveshchensk, Russian Federation, p.A6173 ATS 2019 • Dallas, TX 334 WEDNESDAY • MAY 22