ATS 2019 Virtual Final Program

P1042 Bilateral Upper Lobe Atelectasis with Asthma Exacerbation Causing Acute Hypoxemic Respiratory Failure as a Complication of Bronchial Thermoplasty/ A.S. Ray, K.S. Robinett, V.K. Holden, E. Pickering, A. Sachdeva, Baltimore, MD, p.A6127 P1043 “Saved by Sevo” - Sevoflurane in Refractory Adult Status Asthmaticus/ L. Littlefield, S. Kagunye, L. Jo, V. Balasubramanian, Fresno, CA, p.A6128 P1044 Combined Use of Veno Venous Extracorporeal Life Support and Inhalational Isoflurane Use For Status Asthmaticus/ S. Nandavaram, L. Benninger, V. Scheuble, S. Chandrashekaran, H.M. Alnuaimat, A. Emtiazjoo, T. Machuca, M. Pipkin, A. Pelaez, Lexington, KY, p.A6129 P1045 An Unusual Case of Beta Agonist Induced Lactic Acidosis Masquerading as Diabetic Ketoacidosis/ A. Amin, S. Kwatra, G. Sharma, U. Khalid, M. Shah, Youngstown, OH, p.A6130 P1046 Eosinophils: An Innocent Bystander? A Case of Vanishing Eosinophils with Lingering Severe Asthma/ N.M. Pradhan, L. Rogers, M.B. Beasley, T.J. Harkin, New York, NY, p.A6131 P1047 Should a Low FEV1 Exclude a Severe Asthma Patient from Undergoing Bronchial Thermoplasty? We Do Not Think So/ K.S. Robinett, H.M.N. Abbas, E. Pickering, A. Sachdeva, Baltimore, MD, p.A6132 BASIC • CLINICAL • TRANSLATIONAL THEMATIC POSTER SESSION D32 ACUTE LUNG INJURY AND ARDS: CLINICAL AND MECHANISTIC STUDIES 9:15 a.m. - 3:30 p.m. KBHCCD Area F (Hall F, Level 2) Viewing: Posters will be on display for entire session. Discussion: 11:15-12:00: authors will be present for individual discussion 12:00-1:00: authors will be present for discussion with assigned facilitators. Facilitator : W.J. Janssen, MD, Denver, CO P807 Soluble PD-L1 and PD-1 Concentrations Are Associated with Alveolar Inflammation and Severity of Lung Injury in Subjects with ARDS/ E.D. Morrell, V. Dmyterko, R.D. Stapleton, M.M. Wurfel, C. Mikacenic, Seattle, WA, p.A6133 P808 Genetic Polymorphism of Variable Number Tandem Repeat Region of Mucin 4 Might Have Some Relevance to Severe Lung Injury/ H. Ohta, J. Shiihara, F. Kudo, M. Nomura, Y. Mizushina, O. Fumiyoshi, S. Koyama, K. Hagiwara, Saitama, Japan, p.A6134 P809 Functional Characteristics of Lung Extracellular Vesicles Released from Sterile and Infectious Acute Lung Injury/ H. Lee, D. Zhang, Y. Jin, Boston, MA, p.A6135 P810 CD101 - Eosinophil Serves as an Early Suppressor in Endotoxin-Induced Acute Lung Injury/ C. Zhu, L. Zhou, Q. Weng, S. Ying, Z. Chen, H. Shen, W. Li, Hangzhou, China, p.A6136 P811 Fluorofenidone Attenuates Acute Lung Injury Through Suppressing MyD88/I k B/NF- κ B/NALP3 Pathway/ J. Meng, X. Lv, L. He, L. Tao, Changsha, China, p.A6137 P812 Analysis of Hyperoxic Lung Injury in Mice Deficient in Gene for Cytochrome P450 (CYP)1b1, 1a1 or 1a2/ C. Coarfa, A.C. Veith, M.J. Robertson, K. Lingappan, B. Moorthy, Houston, TX, p.A6138 P813 Targeting the Deubiquitinase STAMBP to Reduce NLRP3 Inflammasome Activity/ J.S. Bednash, T.R. Smail, J.D. Londino, B. Chen, R.K. Mallampalli, Pittsburgh, PA, p.A6139 P814 Alda-1 Attenuates Oxidative Stress-Induced Mitochondrial Aberrations in Acute Lung Injury/ S. Patil, S. Saji, M. Alleyn, M. Borra, H. Hernandez-Cuervo, J. Fukumoto, R. Soundararajan, R.F. Lockey, L. Galam, N.V. Kolliputi, Tampa, FL, p.A6140 Facilitator : S. Grazioli, MD, Geneva, Switzerland P815 Clinical Diagnostic Accuracy of Respiratory Failure in Critically Ill Hematopoietic Stem Cell Transplant Patients/ B.L. Ferreyro, B. Reeta, E.C. Goligher, M.E. Detsky, S. Thyagu, L. Munshi, Toronto, Canada, p.A6141 P816 Muscle Contributes to the Inflammatory Environment Following Lung Injury/ J.J. Bivona, S. Ventrone, B. Guigni, M. Floersch, R.D. Stapleton, D.C. Files, M. Toth, B.T. Suratt, Burlington, VT, p.A6142 P817 Investigating Leukocyte Luminal Dynamics, Diapedesis, and Abluminal Crawling with Optically Transparent Nanoporous Membranes/ A. Salminen, T. Khire, R. Waugh, T. Gaborski, J. McGrath, Rochester, NY, p.A6143 P818 The Effects of Pregnancy on the Pulmonary Response to Lipopolysaccharide-Induced Acute Lung Injury Do Not Appear to Be Due to Changes in Neutrophil Function/ R.E. Rieck, J.J. Bivona, S. Ventrone, M. Floersch, M. Kokoszynska, G.J. Euceda, E.A. Bonney, B.T. Suratt, Burlington, VT, p.A6144 P819 Aging Decreases Tissue Protective Function of Regulatory T Cells in the Lung/ L. Morales-Nebreda, K. Helmin, B.D. Singer, Chicago, IL, p.A6145 P820 Alveolar Regulatory T Cell Kinetics in Patients with Acute Respiratory Distress Syndrome/ D. Norton, M. McCravy, M.K. Tune, T. Devlin, M.B. Drummond, C.M. Doerschuk, J.R. Mock, Chapel Hill, NC, p.A6146 P821 TRPV4 Mediates the Macrophage Phagocytic and Cytokine Response to Leptin/ A. Perelas, R.G. Scheraga, S. Abraham, L. Grove, B.D. Southern, J. Crish, M.A. Olman, Cleveland, OH, p.A6147 P822 Glutamine Metabolism Regulates Neutrophil Clearance and Macrophage Activity in Acute Lung Injury/ C.L. Vigeland, H.S. Beggs, C.M. Doerschuk, Chapel Hill, NC, p.A6148 Facilitator : E.D. Morrell, MD, MA, Seattle, WA P823 Influenza, Lipopolysaccharide, and Particulate Matter Treatment Result in Distinct Metabolic Alterations in Macrophages/ P. Woods, A. Meliton, K.A. Sun, L.M. Kimmig, R.B. Hamanaka, G.M. Mutlu, Chicago, IL, p.A6149 P824 Functional Role of Plet1+ Alveolar Macrophages in Lung Repair After Influenza Virus Induced Injury/ B. Selvakumar, L. Pervizaj-Oruqaj, A.I. Vazquez-Armendariz, M. Heiner, J. Wilhelm, D. Wolff, W. Seeger, J. Lohmeyer, S. Herold, Bad Nauheim, Germany, p.A6150 ATS 2019 • Dallas, TX WEDNESDAY • MAY 22 333 WEDNESDAY MORNING