ATS 2019 Virtual Final Program

710 Risk of Readmission and Mortality Following Admission for Hypercapnic Respiratory Failure/ A. Meservey, M.C. Burton, A.E. Dixon, Burlington, VT, p.A5795 711 Change in Diaphragm Thickness in Mechanically Ventilated Children/ T. Pedigo, J. Hotz, S. Shah, M. Elkhunovich, R.G. Khemani, Los Angeles, CA, p.A5796 712 Transvenous Phrenic Nerve Pacing May Mitigate Ventilation-Induced Diaphragm Atrophy in All Myofiber Types/ K. Fernandez, E. Rohrs, T. Bassi, M. Ornowska, S.C. Reynolds, Burnaby, Canada, p.A5797 713 Qualitative Assessment of the Diaphragm in the Mechanically Ventilated Critically Ill Using Real-Time Shear Wave Ultrasound Elastography/ B. Jung, A. Flatres, Y. Aarab, N. Molinari, S. Matecki, M. Amalric, R. Larcher, S. Jaber, K. Klouche, Montpellier, France, p.A5798 714 Reproducibility of Real-Time Shear Wave Ultrasound Elastography, A New Tool for the Evaluation of Diaphragm and Limb Muscles Stiffness in Critically Ill Patients: Preliminary Results of the Ultramuscle Study/ B. Jung, Y. Aarab, A. Flatres, M. Amalric, J.-J. Tudesq, R. Larcher, D. Chapeau, S. Jaber, K. Klouche, S. Matecki, Montpellier, France, p.A5799 715 Bone Marrow-Derived Macrophages of Duchenne Muscular Dystrophy (mdx) Mice Are Differentially “Educated” Based on Muscle Disease Stage/ S. Bhattarai, F. Liang, Q. Li, E. Kaufmann, M. Divangahi, B.J. Petrof, Montreal, Canada, p.A5800 716 MRI Assessment of Diaphragm Impairment in Duschenne Muscolar Distrophy (DMD): Comparison to Optoelectronic Plethysmography and Pulmonary Function Tests (PFTS)/ A. Aliverti, F. Pennati, F. Arrigoni, A. Lo Mauro, M.G. D’Angelo, Milano, Italy, p.A5801 717 Transvenous Phrenic-Nerve-Stimulated Diaphragm Contraction During Mechanical Ventilation Decreases Loss of End-Expiratory Lung Volume in Non-Injured Lungs/ E. Rohrs, M. Ornowska, T.G. Bassi, K. Fernandez, S. Reynolds, Burnaby, Canada, p.A5802 718 Transvenous Phrenic-Nerve Diaphragm Stimulation Reduces Lung Inflammation in Non-Injured Porcine Lungs During 50 Hours of Mechanical Ventilation/ E. Rohrs, T.G. Bassi, K. Fernandez, M. Ornowska, S.C. Reynolds, Burnaby, Canada, p.A5803 719 In Vivo Susceptibility of Cystic Fibrosis Mice to Inflammation-Induced Diaphragm and Limb Muscle Dysfunction/ B.J. Petrof, E. Gusev, F. Liang, D. Radzioch, Montreal, Canada, p.A5804 720 A Role for Interleukin-6 in the Pathogenesis of Ventilator-Induced Diaphragmatic Dysfunction/ B.J. Petrof, C. Giordano, S. Hussain, F. Liang, Montreal, Canada, p.A5805 721 MitoQ (Mitoquinone Mesylate) Prevents Sepsis Induced Reductions in Diaphragm Strength and Endurance/ G.S. Supinski, E. Schroder, L. Wang, L.A.P. Callahan, Lexington, KY, p.A5806 722 Effect of Hydroxymethylbutyrate and Eicosapentaenoic Acid on Diaphragm and Quadriceps Strength in MICU Patients/ G.S. Supinski, P. Netzel, L.A.P. Callahan, Lexington, KY, p.A5807 723 Role of TLR4 Receptor in Lipopolysaccharide-Induced Decrease of Thiamine Transporter Expression in C2C12 Cells/ C.S. Sassoon, E. Zhu, L. Fang, H.M. Said, Long Beach, CA, p.A5808 724 Treatment Effect of Idebenone on Inspiratory Flow Reserve (IFR) in Patients with Duchenne Muscular Dystrophy (DMD): Long Term Analysis from the SYROS Study/ O.H. Mayer, M. Leinonen, S. Hasham, G. Buyse, Philadelphia, PA, p.A7449 BASIC • BEHAVIORAL RAPID: RAPID ABSTRACT POSTER DISCUSSION SESSION C110 THE FUTURE OF LUNG CANCER BIOMARKERS: WHERE SHOULD WE LOOK? 2:15 p.m. - 4:15 p.m. KBHCCD Arena (Level 2) Abstract Summaries 2:15-2:45 Viewing/Discussion 2:45-4:15 Chairing: J.G. Aerts, MD, PhD, Rotterdam, Netherlands M.M. Fuster, MD, San Diego, CA A.V. Gonzalez, MD, MSc, Montreal, Canada 401 The Advanced Lung Cancer Inflammation Index Is a Prognostic Marker in Patients Undergoing Curative-Intent Therapy for Lung Cancer/ A. Cypro, M.M. Fuster, P.R. Montgrain, San Diego, CA, p.A5809 402 The Utility of Liquid Based Biopsy Using Next Generation Sequencing Technology at the Time of Tissue Collection by Bronchoscopy for Suspected Lung Cancer/ S. Ghadermarzi, P. Chandrika, S. Cowles, J.E. Denis, M.R. Bowling, Greenville, NC, p.A5810 403 Prevalence and Significance of APOBEC-Mediated RNA Editing in Lung Cancer Tumors/ F. Zhang, S. Yendamuri, S. Patnaik, Hanover, NH, p.A5811 404 Detection of T790M Mutation in Blood Versus Tumor Tissue Biopsy/ L. Sakr, G. Kasymjanova, H. Wang, G. Chong, A. Spatz, D.I. Small, C. Pepe, V. Cohen, J. Agulnik, Montreal, Canada, p.A5812 405 Transcriptomic Signatures in Airway Brushings and Lung Cancer Prognosis/ K. Gershner, E. Olsen, R. Schluger, A.S. Scott, A. Sun, H. Beg, Y. Li, T.-A. Yie, I. Sulaiman, B. Wu, J.L. Bessich, S. Rafeq, G.C. Michaud, D.H. Sterman, W.N. Rom, L.N. Segal, J.-C.J. Tsay, New York, NY, p.A5813 406 Reliability of PD-L1 Assays Using Small Tissue Samples Compared with Surgical Specimens/ M.K. Lee, J.S. Eom, Busan, Korea, Republic of, p.A5814 407 Utility of Regional Airway Epithelial Cells for Lung Cancer Biomarker/ B. Kwok, V. Chiang, S. Thomas, S. Alapaty, T.-A. Yie, W.N. Rom, J. Tsay, New York, NY, p.A5815 ATS 2019 • Dallas, TX TUESDAY • MAY 21 309 TUESDAY AFTERNOON

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