ATS 2019 Virtual Final Program

303 Single Nucleotide Polymorphism in the Gene Encoding Macrophage Migration Inhibitory Factor (MIF) and Its Association with Active Pulmonary Tuberculosis/ D. Rossato Silva, M. Gehlen, R.M. Bernardi, C. Anton, F.D. Machado, E.R.D. Costa, M.L.R. Rossetti, Porto Alegre, Brazil, p.A4234 304 A Lung-Oriented Controlled Human Infection Model (CHIM) Using Live BCG and Sterile PPD to Evaluate Tuberculosis Immunopathogenicity/ M. Davids, A. Pooran, F. Thompson, R. Meldau, L. Mottay, A. Esmail, K. Dheda, Cape Town, South Africa, p.A4235 305 Increased Frequency and Modulating Effects of Granulocytic Myeloid-Derived Suppressor Cells on Mycobacterial Survival in Patients with Tuberculosis/ A. Pooran, M. Davids, F. Thompson, K. Dheda, Cape Town, South Africa, p.A4236 306 Immunometabolism Directs Human CD1c-Positive Myeloid Dendritic Cell Responses to BCG Infection/ M. O’Sullivan, D. Triglia Van Nierop, K. Gogan, J. Keane, Dublin, Ireland, p.A4237 307 The Role of Cigarette Smoke-Exposed T Regulatory Cells in Macrophage Control of Mycobacterium Tuberculosis/ E.D. Chan, S. Aerts, A. Musheyev, J.R. Honda, X. Bai, Denver, CO, p.A4238 308 Role of MAIT Cells in Mycobacterium Intracellulare Infection In Vivo/ E.D. Chan, S. Aerts, S. Choi, Y.S. Kwon, M. Brigl, J.R. Honda, J. Matsuda, L. Gapin, X. Bai, Denver, CO, p.A4239 309 An In Vitro Study Simulating Nontuberculous Mycobacteria Infection in the Context of Gastroesophageal Reflux/ J.R. Honda, S.N. Dawrs, M. Kautz, E.D. Chan, Denver, CO, p.A4240 310 The Human Respiratory Epithelium Exhibits a Robust Inflammatory Response to Mycobacterium Abscessus Infection/ S. Mehta, S.L. Brody, S. Khader, St. Louis, MO, p.A4241 311 Microbial Short Chain Fatty Acids Impair Mycobacterium Avium (MAC) Clearance by Alveolar Macrophages/ J. Carpenito, B. Wu, I. Sulaiman, S.G. Kurz, Y. Li, L. Perez, B. Franca, E. Olsen, A. Gonzalez, K. Yie, S. Ma, C. Naidoo, G. Theron, M. Weiden, A. Basavaraj, J.J. Tsay, R. Condos, D.L. Kamelhar, D.J. Addrizzo-Harris, L.N. Segal, New York, NY, p.A4242 312 Role of PD-1 Pathway in Pulmonary MAC Infection Using Mice Model/ M. Nakajima, M. Matsuyama, M. Kawaguchi, M. Sherpa, K. Yoshida, T. Kiwamoto, Y. Matsuno, Y. Morishima, Y. Ishii, N. Hizawa, Tsukuba, Japan, p.A4243 313 NLRP3 Inflammasome Is Attenuated in Patients with Mycobacterium Avium Complex Lung Disease and Correlated with Decreased Il-1ß Response and Host Susceptibility/ C.-C. Shu, M.-F. Wu, C.-J. Yu, Taipei, Taiwan, p.A4244 314 Inflammatory Response Induced by Nontuberculous Mycobacteria Is Associated with Altered Cell Energy Metabolism in Macrophages/ Z. Prasla, B. Bedi, Z. Yuan, R.T. Sadikot, Atlanta, GA, p.A4245 ATS 2019 • Dallas, TX MONDAY • MAY 20 217 MONDAY AFTERNOON