ATS 2019 Virtual Final Program

3:45 Collagen Type IV Degradation Predicts Mortality in the Eclipse COPD Cohort/ H. Jessen, S.R. Ronnow, L. Langholm, N.S. Gudmann, M. Karsdal, T. Manon-Jensen, R. Tal-Singer, B. Miller, J. Vestbo, J.M.B. Sand, D.J. Leeming, Herlev, Denmark, p.A4001 4:00 Video Telehealth Pulmonary Rehabilitation Intervention in COPD Reduces 30-Day Readmissions/ S.P. Bhatt, S.B. Patel, E.M. Anderson, D. Baugh, T. Givens, C. Schumann, J.G. Sanders, S.T. Windham, G.R. Cutter, M.T. Dransfield, Birmingham, AL, p.A7376 BASIC • BEHAVIORAL MINI SYMPOSIUM B94 BEST OF PEDIATRICS 2:15 p.m. - 4:15 p.m. OMNI DALLAS DOWNTOWN Dallas BallroomG (Level 3) Chairing: S.D.M. Dell, MD, Toronto, Canada S.A. McGrath-Morrow, MD, Baltimore, MD Oral Presentations 2:15 Human Lung Organoids as a Novel 3 Dimensional Model System to Study Fetal RSV Infection/ T.J. Harford, B.R. Dye, V. Bokun, C.C. Smallcombe, J.R. Spence, L.D. Shea, F. Rezaee, G. Piedimonte, Cleveland, OH, p.A4002 2:30 Aspergillus and Early CF Lung Disease: Guilty Until Proved Innocent?/ O. Breuer, D. Caudri, A. Schultz, L. Turkovic, S.C. Ranganathan, S.M. Stick, Perth, Australia, p.A4003 2:45 CRISPR/Cas9 Genome Editing Therapy for Hereditary Pulmonary Alveolar Proteinosis/ K. Shima, T. Suzuki, Y. Ma, C. Mayhew, A. Sallese, B.C. Carey, P. Arumugam, B.C. Trapnell, Cincinnati, OH, p.A4004 3:00 Lung Density and Disease Severity of Neonatal Bronchopulmonary Dysplasia: Objective Quantification via Ultrashort Echo-Time MRI and Comparison to Reader Scoring/ N.S. Higano, R.J. Fleck, A.H. Schapiro, M. House, P.S. Kingma, J.C. Woods, Cincinnati, OH, p.A4005 3:15 Circulating MicroRNAs and Treatment Response in CAMP/ J. Li, A. Kho, L. Farnam, R. Chase, S.T. Weiss, K.G. Tantisira, Boston, MA, p.A4006 3:30 Neutrophilic Exosomes as Pathogenic Entiities in Bronchopulmonary Dysplasia/ C.V. Lal, G. Rezonzew, D. Russell, K. Genschmer, N. Ambalavanan, J.E. Blalock, A. Gaggar, Birmingham, AL, p.A4007 3:45 Influence of CFTR Modulators on Immune Responses in Cystic Fibrosis/ B.T. Kopp, S. Zhang, C. Shrestha, Columbus, OH, p.A4008 Featured Speaker 4:00 Pulmonary Outcomes of Bronchopulmonary Dysplasia/ S.A. McGrath-Morrow, Baltimore, MD BASIC • TRANSLATIONAL MINI SYMPOSIUM B95 CELLULAR AND MOLECULAR LANDSCAPE OF THE LUNG 2:15 p.m. - 4:15 p.m. KBHCCD Room D221/D225/D226 (Level 2) Chairing: T.J. Mariani, PhD, Rochester, NY J.P. Bridges, PhD, Cincinnati, OH Z. Borok, MD, ATSF, Los Angeles, CA Oral Presentations 2:15 Epigenomic Analysis of Sox9+ Lung Epithelial Progenitor Cell Specification Defines New Transcriptional Regulatory Networks in Lung Development/ D.T. Swarr, S. Fernandes, D. Khattar, W. Zacharias, M. Gillen, Cincinnati, OH, p.A4009 2:30 Characterization of Neonatal Lung Cells Through Single Cell Genome Sequencing/ S. Bhattacharya, J. Lillis, C. Baker, M. Guo, J.R. Myers, G. Bandopadhyay, S. Romas, R. Misra, J. Dutra, J. Holden-Wiltse, A. Mcdavid, J.A. Whitsett, J. Ashton, Y. Xu, G.S. Pryhuber, T.J. Mariani, Rochester, NY, p.A4010 2:45 Dynamic Single-Cell Chromatin Landscapes of Alveolar Type 1 Cell Populations in the Developing Lung/ T.E. Duong, B. Sos, J.S. Hagood, K. Zhang, San Diego, CA, p.A4011 3:00 Integrated Epigenomic Analysis of the Gene Regulatory Networks Underlying Regenerative Capacity in Alveolar Epithelial Progenitor Cells/ W. Zacharias, M. Morley, D.T. Swarr, P. Senthamarai Kannan, M.C. Basil, E.E. Morrisey, Cincinnati, OH, p.A4012 3:15 The Secondary Crest Myofibroblast PDGFRa Controls Multiple Signaling Networks Involved in Elastogensis During Postnatal Alveolar Formation/ C. Li, M.K. Lee, F. Gao, S. Webster, H. Di, S.M. Smith, G.S. Pryhuber, Z. Borok, S. Bellusci, P. Minoo, Los Angeles, CA, p.A4013 3:30 Single Cell RNA-Seq Identifies TGF-Beta as a Critical Regulator of Alveolar Regeneration/ R. Zemans, N. Jansing, P. Jiang, A. Gillen, R. Fu, A.N. Gerber, E.F. Redente, J.R. Hesselberth, K.A. Riemondy, Ann Arbor, MI, p.A4014 3:45 Development and Function of Airway Tuft Cells in Health and Disease/ M. Kotas, B. Terrier, E.K. Cope, A. Goldberg, S. Pletcher, M.A. Seibold, C. Moore, E.D. Gordon, R. Locksley, San Francisco, CA, p.A4015 4:00 Single Cell Transcriptomics Reveals the Cellular and Molecular Diversity of the Human Tracheal Airway Epithelium in Smokers and Non-Smokers/ K. Goldfarbmuren, N.D. Jackson, N. Dyjack, S.S. Sajuthi, K. Li, C.L. Rios, M.T. Montogomery, J.L. Everman, E.K. Vladar, M.A. Seibold, Denver, CO, p.A4016 ATS 2019 • Dallas, TX MONDAY • MAY 20 205 MONDAY AFTERNOON