ATS 2019 Virtual Final Program

Facilitator : J. Alladina, MD, Boston, MA P705 Modulation of Innate Lymphoid Cell Subsets in a Mouse Model of Isocyanate-Induced Asthma?/ E. Blomme, S. Provoost, L. Pollaris, H.P. Van Eeckhoutte, L. Vandenbroucke, F. Verhamme, G.F. Joos, G.G. Brusselle, J. Vanoirbeek, T. Maes, Ghent, Belgium, p.A2942 P706 Associations of Obstructive Sleep Breathing Disorder (SBD) Features with Inflammation in Patients with Asthma/ N. Liang, O. Broytman, M. Teodorescu, Madison, WI, p.A2943 P707 IL-33/ILC2 Axis in Allergic Asthma and Influenza-Induced Asthma Exacerbation/ L. Ravanetti, A. Dijkhuis, R. Lutter, Amsterdam, Netherlands, p.A2944 P708 Endogenous IL-33 and Its Auto-Amplification of IL-33/ST2 Pathway Play an Important Role in Asthma/ J. Li, J.M. Magat, J.L. Thomas, J.P. Dumouchel, La Jolla, CA, p.A2945 P709 Immune Response and Airway Hyperresponsiveness to Respiratory Syncytial Virus Are Impaired in Viable Atopic Lung Tissue Ex Vivo of Non-Asthmatic Donors/ E.S. Twisterling, S. Dehmel, S. Wronski, P. Braubach, D.D. Jonigk, G. Warnecke, P. Zardo, M. Krüger, K. Sewald, A. Braun, Hannover, Germany, p.A2947 P710 Colony Stimulating Factor 1 and Its Receptor Are New Potential Therapeutic Target for Asthma/ H.-G. Moon, S.-J. Kim, S.J. Ackerman, V. Natarajan, G.Y. Park, Chicago, IL, p.A2948 P711 Development and Characterization of Antisense Oligonucleotides Against Human Rhinovirus for Efficient Prevention of Asthma Exacerbation/ D.P. Potaczek, S.D. Unger, N. Zhang, S. Taka, S. Michel, N. Akdag, F. Lan, M. Helfer, C. Hudemann, M. Eickmann, C. Skevaki, S. Megremis, A. Sadewasser, B. Alashkar Alhamwe, F. Alhamdan, M. Akdis, M.R. Edwards, S.L. Johnston, C.A. Akdis, S. Becker, C. Bachert, N.G. Papadopoulos, H. Garn, H. Renz, Marburg, Germany, p.A2949 P712 Physiologic Response to Chronic House Dust Mite Exposure in Mice Is Dependent on Lot Characteristics/ J. Daly, Z. Yang, J.L. Ingram, R.M. Tighe, L.G. Que, Durham, NC, p.A2950 P713 Myeloid Differentiation Protein-2 Is Involved in House Dust Mite-Mediated Allergic Airway Inflammation with Altered Dendritic Cells Function/ T. Ishii, T. Nagase, N. Yamashita, Tokyo, Japan, p.A2951 Facilitator : R.-E.E. Abdulnour, MD, Boston, MA P714 Degradation of Extracellular Vesicles by Enzymatic Allergens/ M.D. Haggadone, E. Zhang, M. Peters-Golden, Ann Arbor, MI, p.A2952 P715 Diet-Induced Obesity Potentiates Dendropoiesis Via p38 MAPK Activation and Exacerbate Airway Inflammation/ A. Mishra, A.K. Jaiswal, M. Sandey, A. Saxena, P.K. Dagur, J.P. McCoy, S.J. Levine, Auburn, AL, p.A2953 P716 Modulation of TRPV1 in Bronchial Epithelium of Children by PI3 Kinase/ T.J. Harford, L. Grove, V. Bokun, C.C. Smallcombe, F. Rezaee, M.A. Olman, G. Piedimonte, Cleveland, OH, p.A2954 P717 Stanniocalcin-1, a Candidate Epithelium-Derived Relaxing Factor in Asthma/ X. Yao, J. Xu, Y. Meng, M. Jia, Y. Wu, J. Jiang, Y. Yang, X. Yan, I.M. Adcock, M. Huang, Nanjing, China, p.A2955 P718 Eosinophil and Neutrophil Granulocyte Immunophenotyping Using Chipcytometry/ S. Carstensen, O. Holz, J.M. Hohlfeld, M. Müller, Hanover, Germany, p.A2956 P719 Modelling Airway Diffusion Kinetics of Tagged Dextran Complexes to Understand Airway Biology of Inhaled Biological Protein Therapeutics Reveals Marked Anatomical Variation/ G.P. Anderson, G. Ciccotosto, A. Jarnecki, M.J. Chuei, E.-M. Hansbauer, S. Klingl, T. Jaquin, G. Matschiner, S. Olwil, Parkville, Australia, p.A2957 P720 Deletion of Elovl6 Alters Fatty Acid Composition in Lung Tissue and Enhances Allergic Airway Inflammation/ K. Yoshida, Y. Morishima, H. Sakurai, M. Sherpa, Y. Tsunoda, M. Nakajima, M. Matsuyama, T. Kiwamoto, Y. Matsuno, Y. Ishii, N. Hizawa, Tsukuba, Japan, p.A2958 P721 Airway Smooth Muscle-Specific Transcriptomic Signatures of Glucocorticoid Exposure in Asthma and Non-Asthma Donors/ M. Kan, C. Koziol-White, M. Shumyatcher, M. Johnson, W. Jester, R.A. Panettieri, B.E. Himes, Philadelphia, PA, p.A2959 P722 Regulation of Airway Inflammation by Arginine Metabolic Pathways for Nitric Oxide Synthesis and Mitochondrial Arginase/ K. Asosingh, K. Weiss, M. Frimel, N. Wanner, M. Alemagno, S. Kessler, D.A. Meyers, W. Xu, S.C. Erzurum, Cleveland, OH, p.A2960 P723 Mitochondrial DNA Variation and Severe Asthma/ W. Xu, R. Chen, B. Hu, J.G. Zein, C. Liu, S.A.A. Comhair, M.A. Aldred, G.A. Hawkins, D.A. Meyers, E.R. Bleecker, M. Castro, N.N. Jarjour, L.C. Denlinger, J.V. Fahy, W.C. Moore, S.E. Wenzel, W. Phipatanakul, E. Israel, B.M. Gaston, S.C. Erzurum, Cleveland, OH, p.A2961 BASIC • CLINICAL • TRANSLATIONAL THEMATIC POSTER SESSION B34 ALLERGIC DISEASE: CLINICAL STUDIES AND MECHANISMS 9:15 a.m. - 4:15 p.m. KBHCCD Area A (Hall F, Level 2) Viewing: Posters will be on display for entire session. Discussion: 11:15-12:00: authors will be present for individual discussion 12:00-1:00: authors will be present for discussion with assigned facilitators. Facilitator : A.P. Fontenot, MD, Aurora, CO P1 Serum Biomarkers in Allergic Bronchopulmonary Aspergillosis/ A. Prithvi, M. Singh, J. Mathew, A. Chakrabarti, Chandigarh, India, p.A2962 P2 Utility of Fractional Exhaled Nitric Oxide (FeNO) Levels in Differentiating Upper Respiratory Tract Infection and Bronchial Asthma from Healthy Normal School Children/ C.A. Gorme, Quezon City, Philippines, p.A2963 P3 The Positioning of Measurements of Serum YKL-40 in Various Respiratory Diseases/ C. Nakano, Tokyo, Japan, p.A2964 ATS 2019 • Dallas, TX MONDAY • MAY 20 147 MONDAY MORNING