ATS 2019 Virtual Final Program

117 Whole-Genome Rare-Variant Association Analyses of Sleep-Disordered Breathing Traits in the NHLBI Trans-Omics in Precision Medicine (TOPMed) Consortium/ B.E. Cade, J. Lee, T. Sofer, M. Zhang, S. Redline, Boston, MA, p.A7368 118 Hypoxic Burden Predicts Incident Heart Failure in Adults with Sleep Apnea: The Sleep Heart Health Study/ A. Azarbarzin, S.A. Sands, L. Taranto Montemurro, D. Vena, T. Sofer, S.-W. Kim, D.P. White, D.A. Wellman, S.S. Redline, Boston, MA, p.A7369 BASIC • CLINICAL • TRANSLATIONAL THEMATIC POSTER SESSION B31 LUNG TRANSPLANTATION: CLINICAL AND MECHANISTIC STUDIES 9:15 a.m. - 4:15 p.m. KBHCCD Area B (Hall F, Level 2) Viewing: Posters will be on display for entire session. Discussion: 11:15-12:00: authors will be present for individual discussion 12:00-1:00: authors will be present for discussion with assigned facilitators. Facilitator : M.R. Nicolls, MD, Palo Alto, CA P133 The Biphasic Flow-Volume Loop in Patients with Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis with a History of Lung Transplant: Its Prevalence and Significance/ B. Liu, A. Baydur, Los Angeles, CA, p.A2880 P134 HIF1 a -Mediated Lymphangiogenesis Influences Airway Transplant Rejection/ A.B. Tu, X. Jiang, A. Tian, P. Dahms, P. Zhang, S. Pasupneti, M.R. Nicolls, Palo Alto, CA, p.A2881 P135 Donor Lung Regeneration Through Selective Replacement of Damaged Airway Epithelium/ J. Kim, J. O’Neill, B. Guenthart, A. Hozain, Y. Tipograf, M. Pinezich, M. Bacchetta, G. Vunjak-Novakovic, Hoboken, NJ, p.A2882 P136 Hyperpolarized [1-13C] Pyruvate Magnetic Resonance Imaging of Post-Transplant Allogeneic Rats with Acquired Immune Tolerance/ S. Siddiqui, F. Sertic, M. Pourfathi, S. Rostami, Y. Xin, I. Duncan, S. Kadlecek, A. Naji, R.R. Rizi, Philadelphia, PA, p.A2883 P137 Long-Term Assessment of Lung Function in an Orthotopic Lung Transplant Model Using Multibreath Hyperpolarized Gas Imaging/ S. Siddiqui, Y. Xin, H. Hamedani, F. Amazajerdian, M. Pourfathi, F. Sertic, I. Duncan, S. Kadlecek, R.R. Rizi, Philadelphia, PA, p.A2884 P138 The Role of B-Cells in an Experimental Murine of Restrictive Allograft Syndrome/ K. Misumi, Y. Aoki, D.S. Wheeler, T. Mimura, D. Kreisel, N. Walker, V.N. Lama, Ann Arbor, MI, p.A2885 P139 Lung Ultrasound to Detect Allograft Dysfunction in Lung Transplant Recipients/ T. Narula, A. Banga, D. Sahoo, S. Krishnan, X. Han, X. Wang, M.M. Budev, A.C. Mehta, A. Moghekar, Jacksonville, FL, p.A2886 Facilitator : R.G. Barbers, MD, ATSF, Los Angeles, CA P140 LGM2605 Reduces Inflammatory Phenotype of the Pulmonary Vasculature Following Ischemia/Reperfusion Using an Ex Vivo Mouse Lung Perfusion System/ M. Christofidou-Solomidou, K. Park, J.-Q. Tao, R. Pietrofesa, T. Sielecki, S. Chaterjee, Philadelphia, PA, p.A2887 P141 Predictive Biomarkers for Allograft Injury Post Lung Transplantation/ V. Kaza, C. Zhu, L. Feng, A. Reddy, L.S. Terada, A. Banga, S. Bollineni, J. Mullins, M. Mohanka, F. Torres, Q.-Z. Li, Dallas, TX, p.A2888 P142 Cytokine and Microparticle Analysis in Lung Transplant Recipients Treated with Basiliximab Induction Immunosuppression: An Observational Study/ J. Hallsten, L.J. Kang, A. Rodrigues, W. Jeske, J. Walenga, W.T. Vigneswaran, Maywood, IL, p.A2889 P143 Combined Airway Transcriptome Analysis and Immune Proteome Profiling of the Lung Allograft Identifies a Type-1 Immune Signature and Indoleamine 2,3-Dioxygenase 1 (IDO1) as a Potential Biomarker of Chronic Lung Allograft Dysfunction/ J. Wei, A. Hoji, C. Iasella, A. Ferguson, N. Jain, Y. Zhang, M. Brown, E.A. Lendermon, B. Johnson, S.D. Kilaru, J.M. Pilewski, M.R. Morrell, W. Chen, K. Chen, J.F. McDyer, Pittsburgh, PA, p.A2890 P144 Nintedanib as Bridge Therapy to Retransplantation for Restrictive Allograft Syndrome: A Case Report/ S. Ghirardo, A. Di Mascio, M. Maschio, E. Barbi, Trieste, Italy, p.A2891 P145 Does Calcineurin Inhibitors (CNIs) Sparing Regimen Improve Kidney Function in Patients Post Lung Transplantation?/ C.R. Ju, Q. Lian, B. Wei, X. Xu, R. Chen, J. He, Guangzhou, China, p.A2892 BASIC • CLINICAL • TRANSLATIONAL THEMATIC POSTER SESSION B32 ASTHMA: MECHANISMS OF DISEASE I 9:15 a.m. - 4:15 p.m. KBHCCD Area E (Hall F, Level 2) Viewing: Posters will be on display for entire session. Discussion: 11:15-12:00: authors will be present for individual discussion 12:00-1:00: authors will be present for discussion with assigned facilitators. Facilitator : T.L. Bonfield, PhD, Cleveland, OH P655 Aerosolized Toll-Like Receptor Agonists Suppress House Dust Mite Allergic Asthma/ D.L. Goldblatt, G. Valverde, S. Tkachman, M. Martinez-Mocygemba, D.P. Huston, M.J. Tuvim, B.F. Dickey, S.E. Evans, Houston, TX, p.A2893 P656 An Effect of Novel Non-Antibiotic Macrolide EM900 in HDM-Induced Airway Inflammation Mice Model/ K. Takahashi, H. Sadamatsu, H. Tashiro, Y. Noguchi, S. Omura, S. Kimura, T. Sunazuka, N. Sueoka-Aragane, Saga, Japan, p.A2894 ATS 2019 • Dallas, TX 144 MONDAY • MAY 20