ATS 2020 Advance Program

2:45 Immune Modulation of Lung Epithelial Responses During Influenza Infection D.A. Pociask, PhD, New Orleans, LA 3:15 Roles for AT1 Cells in Lung Generation and Regeneration J. Chen, PhD, MHS, Houston, TX 3:45 Optical Imaging of Regenerative Processes Both in Vitro and in Vivo M.J. Suter, PhD, Boston, MA BASIC • TRANSLATIONAL SCIENTIFIC SYMPOSIUM A86 BUILDING RESPIRATORY EPITHELIUM AND TISSUE FOR HEALTH (BREATH): ORGANOIDS AND ENGINEERING Assembly on Respiratory Cell and Molecular Biology 2:15 p.m. - 4:15 p.m. Target Audience Researchers, clinicians, and trainees. Objectives At the conclusion of this session, the participant will be able to: • understand current efforts to characterize human lung cell biology; • learn about the newest lung organoid culture techniques being used to study lung progenitor cells and to model lung disease; • discuss the development of cutting-edge platforms and bioengineered materials that will facilitate future regenerative medicine. This session is organized to highlight cutting-edge developments in progenitor cell biology and engineering that are paving the way for future regenerative medicine for lung disease. Topics include organoid cultures; epithelial, immune and mesenchymal cell interactions in disease; engineering approaches to model and derive tissue; and progenitor cell biology. The session will culminate with a lung disease patient perspective. This session will educate physicians and basic researchers with illustrations of collaborative multidisciplinary studies. Chairing: Z. Borok, MD, ATSF, Los Angeles, CA S. Janes, PhD, London, United Kingdom O. Eickelberg, MD, ATSF, Aurora, CO 2:15 Disease Specific Challenges for Regeneration Z. Borok, MD, ATSF, Los Angeles, CA 2:40 3DPrinting and Engineering the Matrix for Repair P. de Coppi, MD, PhD, London, United Kingdom 3:00 Organoid Models of Cell-Cell Interactions in Lung Disease C. Kim, PhD, Boston, MA 3:20 Human Embryonic Lung Progenitor Cell Biology M. Nikolic, MD, PhD, Cambridge, United Kingdom 3:40 Precision Cut Lung Slices for Regenerative Medicine Approaches M. Koenigshoff, MD, PhD, ATSF, Aurora, CO 4:00 LivingwithLungDisease andHope for the Future Speaker To Be Announced CLINICAL • TRANSLATIONAL SCIENTIFIC SYMPOSIUM A87 CONTROVERSIES IN PEDIATRIC PULMONOLOGY Assemblies on Pediatrics; Allergy, Immunology and Inflammation; Clinical Problems; Critical Care; Pulmonary Infections and Tuberculosis 2:15 p.m. - 4:15 p.m. Target Audience Pediatric pulmonologists, neonatologists, pediatricians, intensivists, infectious disease specialists, cardiologists, respiratory therapists, nurse practitioners, physician assistants, and nurses. Objectives At the conclusion of this session, the participant will be able to: • identify the benefits, limitations and risks of lung biopsy in identifying and treating rare lung diseases; • improve the antibiotic stewardship without compromising thetreatment of chronic respiratory symptoms; ATS 2020 • Philadelphia, PA 58 SUNDAY • MAY 17