ATS 2020 Advance Program

3:55 Targeting Glucagon-Like Peptide 1 Receptor K. Cahill, MD, Nashville, TN BASIC • TRANSLATIONAL SCIENTIFIC SYMPOSIUM C91 INTEGRATIVE GENOMICS STRATEGIES FOR COMPLEX RESPIRATORY DISEASES Assemblies on Allergy, Immunology and Inflammation; Pediatrics; Pulmonary Circulation; Respiratory Cell and Molecular Biology; Respiratory Structure and Function; Sleep and Respiratory Neurobiology; Thoracic Oncology 2:15 p.m. - 4:15 p.m. Target Audience This symposium is relevant to all ATS assemblies, as well as all basic and clinical scientists, translational researchers, informatics researchers and clinicians interpreting genomic results. Objectives At the conclusion of this session, the participant will be able to: • learn fundamental concepts and analytic strategies related to different omics data types; • understand and learn about systems biology methods that have been used to integrate omics data; • learn of specific examples in which integrative analyses have been used to study lung diseases. Across all respiratory, critical care and sleep medicine, a deluge of omics data (including genomics, transcriptomics, proteomics) is being generated to identify novel biologic disease mechanisms. This symposium will present state of the art methods and applications in integrative genomics, which is based on the principle that biologic mechanisms involve multiple molecular data types and that understanding the interplay between omics data types will accelerate the identification of functional mechanisms that underlie observed genetic association signals. Speakers will provide examples across disparate respiratory and sleep conditions in which integration of omics data has improved our Chairing: B.E. Himes, PhD, Philadelphia, PA M.H. Cho, MPH, MD, Boston, MA S. Sharma, MD, MPH, Aurora, CO 2:15 Insights into the Complexity and Diversity of Cell Populations in IPF and COPD Using Single Cell RNA-Seq I.O. Rosas, MD, Houston, TX 2:35 Network Approaches to Understanding the Omics of Pulmonary Vascular Disease W.M. Oldham, MD, PhD, Boston, MA 2:55 Graph-Based Methods for Systems Discovery in the Lung P.T. Benos, PhD, Pittsburgh, PA 3:15 Integrative Analyses of Omics Data to Understand Asthma Drug Response B.E. Himes, PhD, Philadelphia, PA 3:35 Leveraging Pleiotropy to Discover and Interpret Genetic Associations With Sleep-Disordered Breathing B.E. Cade, PhD, Boston, MA 3:55 Multi-Omic Assessments of Tumor and the Microenvironment in Non-Small Cell Lung Cancer S.M. Dubinett, MD, Los Angeles, CA BEHAVIORAL SCIENTIFIC SYMPOSIUM C92 UNCOVERING THE HIDDEN CURRICULUM: ADDRESSING IMPLICIT BIAS IN MEDICINE Assembly on Behavioral and Health Services Research; Education Committee 2:15 p.m. - 4:15 p.m. Target Audience All physicians, nurses, medical students, respiratory therapists, physical therapists, and social workers, and administrators involved in patient care, education, or recruitment. ATS 2020 • Philadelphia, PA TUESDAY • MAY 19 121