ATS 2020 Advance Program

• Describe various cell types that are involved in the development of COPD. • Describe possible endotypes of COPD. Chronic obstructive pulmonary disease (COPD) is a syndrome that comprises several lung pathologies, but sub-phenotyping the various disease subtypes has not been successful. Functional studies of these polymorphisms suggest that susceptible airway, endothelial, hematopoietic, or smooth muscle cells initially may generate COPD endotypes that are characterized by distinct pathobiological mechanisms. These endotypes may ultimately manifest themselves as emphysematous destruction of the lung. Polymorphisms in cells other than those listed may remain to be identified and could represent yet other endotypes of COPD. Chairing: I. Petrache, MD, ATSF, Denver, CO Y. Tesfaigzi, PhD, Boston, MA P. Woodruff, MD, MPH, San Francisco, CA 2:15 A Patient's Perspective Speaker To Be Announced 2:20 Macrophage Susceptibility and COPD P. Woodruff, MD, MPH, San Francisco, CA 2:39 Susceptibility of Endothelial Cells in COPD I. Petrache, MD, ATSF, Denver, CO 2:58 Susceptibility of Airway Epithelia Drives Chronic Bronchitis and COPD Y. Tesfaigzi, PhD, Boston, MA 3:17 Deficiency in B Cells in COPD F. Kheradmand, MD, Houston, TX 3:36 Dendritic Cells as Origins of COPD Development J.L. Curtis, MD, ATSF, Ann Arbor, MI 3:55 How Understanding Susceptible Cell Types Can Help Improve Clinical Intervention S.I. Rennard, MD, Omaha, NE BASIC • CLINICAL • TRANSLATIONAL SCIENTIFIC SYMPOSIUM B92 ATS JOURNALS 2020 AND BEYOND: TRANSFORMATIONS IN MEDICAL PUBLISHING FOR AUTHORS AND READERS ATS Journals/Publications Policy Committee 2:15 p.m. - 4:15 p.m. Target Audience This session is for researchers just starting their careers and those directing research groups. It will be of interest to those delegates wishing to submit papers, understand the rigorous peer review process, or become future editors. Objectives At the conclusion of this session, the participant will be able to: • improve skills in writing and preparing manuscripts and statistical analysis; • learn about issues with data sharing and preprint servers, and understand publication ethics and how they can impact a submission; • understand how a journal processes, checks, and reviews submitted manuscripts, including trial registration, plagiarism, and image forensics. This session will offer information on submitting papers to the ATS journals, including writing and statistical tips; insight into how the journals work, including peer review, plagiarism, and image forensics; and recent issues that affect the journals, such as data sharing, publication ethics, and preprint servers. Editors will explain how to peer review a paper and how editors review and assess papers for publication. Additionally, this session will provide an opportunity to hear from the editor of ATS Scholar on the objectives of this new, modern journal. Chairing: B.D. Levy, MD, ATSF, Boston, MA J.A. Wedzicha, MD, ATSF, London, United Kingdom K.M. Ridge, PhD, Chicago, IL ATS 2020 • Philadelphia, PA MONDAY • MAY 18 95