ATS 2019 Virtual Final Program

P386 Initial Development of a Mobile Health Tool to Objectively Measure Respiratory Distress in Infants/ L. Stanberry, J. Poli, D. Rich, C. Howard, J. Roberts, R. DiBlasi, J.K. McGuire, M. Rosenfeld, T.N. Hansen, A. von Saint Andre-von Arnim, Minneapolis, MN, p.A2242 P387 Modeling Immunogenicity of Palm Pollen and Mold Spores on Lung Epithelial Cells Using a Lung-On-Chip Technology/ G. Urdaneta, C. Zhang, H. Asif, D. Menendez, N. Kumar, M. Mirsaeidi, Miami, FL, p.A2243 P388 Bioprinted 3D Model to Study the Crosstalk Between Lung Mesenchymal Stem Cells and Lung Extracellular Matrix/ R. Farre, J. Otero, B. Falcones, E. Marhuenda, I. Almendros, D. Navajas, Bercelona, Spain, p.A2244 P389 The Impact of Delay to Inhalation on Drug Delivery: A Laboratory Study Comparing Metered Dose Inhaler (MDI) and MDI/Valved Holding Chamber (VHC) Systems/ J. Suggett, V. Wang, V. Avvamoukova, M. Nagel, London, Canada, p.A2245 Facilitator : B. Suki, PhD, Boston, MA P390 Anatomically Derived Airway Models to Facilitate Computational Toxicology in Mice: Differences in Strains, Gender and Aerosol Particle Deposition/ R.W. Glenny, M.A. Krueger, C. Bauer, R.R. Beichel, Seattle, WA, p.A2246 P391 Pulmonary Fate and Consequences of Albumin- and Transferrin-Coated Gold Nanoparticles/ N. Konduru, K. Zagorovsky, D. Diaz-Diiestra, F. Fisol, M. Sanches, A. Swami, J.D. Brain, R. Molina, Boston, MA, p.A2247 P392 The Establishment of Two Animal Models of Benign Airway Stenosis and the Therapeutic Effect of Mitomycin C on Airway Stenosis/ Z. Cai, F. Li, Shijiazhuang, China, p.A2248 P393 Differentiation of Airway Structure and Lung Function in a Korean Asian Vs. White American Cohort Via Quantitative CT-Based Variables/ H.B. Cho, C.H. Lee, K.J. Chae, G.Y. Jin, J. Choi, C.-L. Lin, E.A. Hoffman, S.E. Wenzel, M. Castro, S.B. Fain, N.N. Jarjour, M.L. Schiebler, R.G. Barr, N.N. Hansel, C.B. Cooper, E.C. Kleerup, M.K. Han, P. Woodruff, R.E. Kanner1, E.R. Bleecker, S.P. Peters, W.C. Moore, S. Cho, Daegu, Korea, Republic of, p.A2249 P394 Markov Chain Simulation of Particle Deposition in the Lung/ A.H. Sonnenberg, B. Suki, Boston, MA, p.A2250 P395 An Analytical Model for a Thick-Walled Alveolus Undergoing Large Deformation Replicates Macroscopic Lung Behavior and Provides Implications for Proper Alveolar Stress and Pressure Calculations/ S.A.M. Bou Jawde, D. Casey, F. Vicario, J.H.T. Bates, B. Suki, Boston, MA, p.A2251 P396 A Postnatal Increase of the Fractal Dimension of the Pulmonary Rat Acini Indicates a Non-Uniform Acinar Development and an Increase of Acinar Complexity/ J.C. Schittny, I. Vogiatzis Oikonomidis, D. Haberthür, M. Stampanoni, Bern, Switzerland, p.A2252 P397 A Multi-Scale Lung Model to Study Heterogeneous Ventilation During the Multiple-Breath Washout Test/ P. Anagnostopoulou, D. Hasler, P. Latzin, D. Obrist, J.C. Schittny, Bern, Switzerland, p.A2253 Facilitator : J.H.T. Bates, PhD, DSc, ATSF, Burlington, VT P398 A Time-Dependent Network Model with Recruitable Edematous Alveoli/ M.M. Mellenthin, R.K. Albert, K.L. Hamlington, J.H.T. Bates, B.J. Smith, Aurora, CO, p.A2254 P399 Assessing the Link Between Viscoelasticity and Extracellular Matrix Composition in the Lung Using A Network Model/ A. Iravani, A. Thambyah, K.S. Burrowes, Grafton, New Zealand, p.A2255 P400 Parenchymal Mechanics and Aging: A Random Fiber Network/ D. Casey, S.A.M. Bou Jawde, B. Suki, J.H.T. Bates, Burlington, VT, p.A2256 P401 Modeling Elastin Fiber Digestion as a Set of Self-Interacting Molecules Capable of Unfolding Binding Sites During Stretch/ S. Amin, B. Suki, Boston, MA, p.A2257 P402 Airflow and Pressure Distribution for Healthy Subjects vs. Asthmatic Patients with 1-D Computational Fluid Dynamics Model/ S. Yoon, S. Choi, C. Zou, J. Choi, M.H. Tawhai, E.A. Hoffman, C.-L. Lin, Daegu, Korea, Republic of, p.A2258 P403 Modeling Flow Dynamics in Neonatal Subglottic Stenosis/ M.M.-C. Yang, A. Bates, E. Hysinger, J.C. Woods, Cincinnati, OH, p.A2259 P404 A Compartment-Based Model of Absolute Lung Ventilation Using Hyperpolarized Gas MRI/ H. Hamedani, Y. Xin, K. Ruppert, S. Kadlecek, F. Amzajerdian, H. Profka, S. Siddiqui, M. Pourfathi, L. Loza, T. Achekzai, I. Duncan, M. Cereda, R. Baron, F. Sertic, F. Bermudez, R.R. Rizi, Philadelphia, PA, p.A2260 P405 Quantifying Ventilation Inhomogeneity Using Hyperpolarized Gas MRI/ H. Hamedani, Y. Xin, K. Ruppert, S. Kadlecek, F. Amzajerdian, H. Profka, M. Pourfathi, S. Siddiqui, L. Loza, T. Achekzai, R. Baron, M. Cereda, I. Duncan, F. Sertic, F. Bermudez, R.R. Rizi, Philadelphia, PA, p.A2261 Facilitator : R. Krishnan, PhD, MS, Boston, MA P406 Observing the Differences in Regional Ventilation Between Dual-CT and Free-Breathing Image Acquisition/ A. Fouras, C.R. Samarage, Westlake Village, CA, p.A2262 P407 Deep Learning-Based Identification of the CT-Derived Primary Airway Branch Variants Associated with COPD: SPIROMICS Cohort/ A. Motahari, B. Smith, R.G. Barr, M.K. Han, J. Schroeder, A.P. Comellas, E.R. Bleecker, D. Couper, C.B. Cooper, R.E. Kanner, F.J. Martinez, P. Woodruff, E.A. Hoffman, Iowa City, IA, p.A2263 P408 Longitudinal MRI Measures of Lung Density and Lung Clearance Index in Normal Subjects Are Highly Repeatable/ R.J. Theilmann, A.R. Elliott, D.J. Conrad, B.A. Bailey, J.M. Fine, C.J. Darquenne, La Jolla, CA, p.A2264 P409 A Novel Method for Quantification of Expiratory Airtrapping Independent of Expiration Level/ L. Gallardo Estrella, S.P. Bhatt, E.M. van Rikxoort, S.M. Humphries, E. Pompe, D.A. Lynch, J.-P. Charbonnier, Nijmegen, Netherlands, p.A2265 P410 Extraction and Imaging of the Canine Acinus Using Micro-CT Imaging/ A. Coats, C.C. Hsia, E.A. Hoffman, Iowa City, IA, p.A2266 ATS 2019 • Dallas, TX SUNDAY • MAY 19 87 SUNDAY MORNING