ATS 2019 Virtual Final Program

P788 Wixela ® Inhub ® Dry Powder Inhaler - In Vitro Performance Compared with Advair ® Diskus ® and Inhalation Profiles in Patients with Asthma or Chronic Obstructive Pulmonary Disease/ A. Cooper, C. Newcomb, R. Wallace, K. Canham, J. Ward, R. Allan, M. Berry, J. Parker, E. Clift, Sandwich, United Kingdom, p.A2207 Facilitator : K.C.W. Wang, PhD, Crawley, Australia P789 Equivalent Systemic Exposure to Fluticasone Propionate/Salmeterol Following Single Inhaled Doses of Advair ® Diskus ® and Wixelar Inhubr: Results of Three Pharmacokinetic Equivalence Studies/ J.K. Ward, N. Wood, R. Allan, S. Haughie, Sandwich, United Kingdom, p.A2208 P790 Effectiveness of a Vibrating Mesh Aerosolizer Compared to a Jet Nebulizer for the Delivery of Bronchodilator Therapy to Acute Adult Asthmatics in the Emergency Department a Randomized Controlled Trial/ H. Chweich, N. Idrees, L. Rice, J. Rideout, B. Barnewolt, S. Kamlarz, F. Tamimi, N.S. Hill, Boston, MA, p.A2209 P791 Validation of the VitalFlo Portable Spirometer in Adolescents with Asthma/ M. Hernandez, K. Mills, S. Ivins, B. Ring, M. Sims, L. Marshall, J. Dieffenderfer, A. Burbank, Chapel Hill, NC, p.A2210 P792 Value and Safety of High Flow Oxygenation in the Treatment of Inpatient Asthma, a Randomized, Double-Blind, Clinical Trial/ A. Fakharian, S. Raeisi, Tehran, Iran, Islamic Republic of, p.A2211 P793 Phase IIb Study of Umeclidinium Versus Placebo in Patients with Asthma/ S. Pascoe, E. Kerwin, K. Cooper, Z. Bailes, R. Nathan, D. Bernstein, A. Fowler, L. Lee, Collegeville, PA, p.A2212 P794 Comparison of Aerosol Dispersion Test with Standard Clinical Measures in Adult Asthmatic Patients/ R.G. Sangani, S. Hadique, T. Petitte, M. McCawley, Morgantown, WV, p.A2213 Facilitator : L. Wang, PhD, Vancouver, Canada P795 Improvement of Simulated Aerosol Deposition Efficiency in Asthmatic Subjects by Altering Particle Inhalation Time/ K. Poorbahrami, D. Mummy, S.B. Fain, J.M. Oakes, Boston, MA, p.A2214 P796 Risk of Pulmonary Embolism in Patients with Asthma: A Meta-Analysis/ S. Congrete, B. Boonpheng, Boston, MA, p.A2215 P797 Functional Small Airways Disease Derived from Parametric Response Mapping Associates with Eosinophilic Asthma/ J. Grace, A.B. Fortuna, M.K. Han, C.J. Galban, N. Lugogo, Ann Arbor, MI, p.A2216 P798 Cardiorespiratory Responses to Exercise Differs in Children with Large and Small Airway Obstructive Disease/ Y. Selvadurai, B. Kennedy, E. Coward, S. Haggie, H. Selvadurai, Sydney, Australia, p.A2217 P799 Intermittent Right to Left Shunting in Asthma Exacerbation Causing Hypoxemia/ W.H. Ahangar, J.P. Sta. Cruz, M. Rives-Sanchez, N. AlQsous, P.K. Valestra, Philadelphia, PA, p.A2218 P800 The Relationship Between Bronchodilator Response and Gas Trapping in Patients with Asthma/ N. Wiebe, M.H. Khan, K.R. Chapman, Vancouver, Canada, p.A2219 Facilitator : K.O. Tonga, MBChB, Sydney, Australia P801 The Opening Index to Measure Airway Closure in Children and Adults with Asthma/ J. Lang, E. McGuire, R. Henderson, J.T. Holbrook, Durham, NC, p.A2220 P802 Changes in Tidal Volume During Exercise Induced Bronchoconstriction (EIB) Could Explain the Post-Exercise Onset of Severe Constriction/ T. Winkler, S.D. Anderson, Boston, MA, p.A2221 P803 Cluster-Guided Image Matching Analysis of Multiscale Lung Response to Bronchial Thermoplasty/ J. Choi, S. Choi, F. Li, E.A. Hoffman, M. Castro, C. Hall, C. Goss, P. O’Shaughnessy, S. McEleney, J. Sieren, C.-L. Lin, Iowa City, IA, p.A2222 P804 Lung Elastic Recoil and Acinar Ventilation Heterogeneity in Older Non-Smokers with Asthma and Fixed Airflow Obstruction/ K. Tonga, N. Berend, C. Thamrin, C.S. Farah, K. Jetmalani, D. Chapman, G.G. King, Sydney, Australia, p.A2223 P805 Small Airway Dysfunction Correlates with Perceived Respiratory Symptoms, Neutrophilic Airway Inflammation and Poor Responses to Anti-Asthma Therapy/ G. Wang, Y. Liu, L. Zhang, H. Li, B. Liang, J. Wang, X. Zhang, Z. Chen, H. Zhang, M. Xie, L. Wang, G. Wang, O. Brian, Chengdu, China, p.A7335 P806 Monitoring Asthma Control with Inhaled Corticosteroids (ICS) Using Airway Hyperresponsiveness (AHR) to Mannitol Compared to Routine Spirometry in a Pulmonary Function Laboratory (PFL)/ C.D. Lake, K.K. Wong, J.D. Brannan, Camperdown, Australia, p.A7336 BASIC • CLINICAL • TRANSLATIONAL THEMATIC POSTER SESSION A65 OBESITY 9:15 a.m. - 4:15 p.m. KBHCCD Area C (Hall F, Level 2) Viewing: Posters will be on display for entire session. Discussion: 11:15-12:00: authors will be present for individual discussion 12:00-1:00: authors will be present for discussion with assigned facilitators. Facilitator : U. Peters, MSc, PhD, Burlington, VT P364 The Effect of Body Mass Index on Lung Volumes in Severe Obesity/ J. Meurling, R. Anglin, L. Howlin, E. O’ Malley, C. Dunlevy, D. O’ Shea, J.F. Garvey, Dublin, Ireland, p.A2224 P365 Effects of Diet Induced Obesity in Lung Alterations in Mice/ T. Pereira, C. Dias, P. Cassanelli, F. Santana, N.T.S. Souza, S.D.O. Santos, M. Kubota, C. Mendes da Silva, I. Tiberio, D. Estadella, V.L. Flor, L. Caperuto, C. Prado, Santos, Brazil, p.A2225 P366 Distinct Physiological Signature of Late-Onset Non-Allergic Asthma of Obesity/ U. Peters, D.A. Kaminsky, R. Walsh, C.M. Kinsey, E. Maclean, N. Daphtary, K. Hodgdon, J.H.T. Bates, A.E. Dixon, Burlington, VT, p.A2226 ATS 2019 • Dallas, TX SUNDAY • MAY 19 85 SUNDAY MORNING

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