ATS 2019 Virtual Final Program

P117 Therapeutic Targeting of Bruton’S Tyrosine Kinase for the Treatment of Acute Lung Injury/ A. Kurdowska, A.Jeffers, W. Qin, J. M. Florence, T.A.Tucker, Tyler, TX, p.A1695 P118 Perfluorochemical-Facilitated Fibrinolysin Delivery: Sustained Improvement in Physiologic Outcomes in Inhalational Smoke Induced Acute Lung Injury (ISALI) in Sheep/ M.R. Wolfson, P. Enkhbaatar, S. Fukuda, C.L. Nelson, R.O. Williams, III, S. Hengsawas, S. Sahakijpijarn, A.A. Komissarov, G. Florova, K.P. Singh, S.I. Idell, T.H. Shaffer, III, Philadelphia, PA, p.A1696 P119 Tumor Necrosis Factor Soluble Receptor Treatment Improves Survival with B. Anthracis Cell Wall Peptidoglycan Challenge in Rats/ X. Cui, Y. Li, J. Shiloach, J. Sun, D. Suffredini, L. Margoles, Y. Fitz, P. Eichacker, Bethesda, MD, p.A1697 P120 The Effects of Obesity on Outcome in PreClinical Animal Models of Infection and Sepsis: A Systematic Review and Meta-Analysis/ X. Cui, W. Xu, D.J. Pepper, J. Sun, J. Welsh, P. Eichacker, Bethesda, MD, p.A1698 P121 Sepsis-Induced Multiorgan Dysfunction Rapidly Progresses in Male Sheep than in Female Sheep/ K. Liu, Y. Niimi, S. Fukuda, T. Baljinnyam, D.S. Prough, P. Enkhbaatar, Galveston, TX, p.A1699 P122 Characterization of Murine Delivery of Aerosolized Therapeutics/ E.S. Halstead, T.M. Umstead, Hershey, PA, p.A1700 Facilitator: A. Fox-Robichaud, BSc, MSc, MD, FRCPC, Hamilton, Canada P123 Respiratory Epithelial Cell Transcriptomics to Identify Endotypes in Pediatric ARDS/ B.M. Varisco, J.G. Williams, R. Joshi, R. Jones, L. Benken, Cincinnati, OH, p.A1701 P124 Ventilatory Pattern Variability and Cardioventilatory Coupling in Rats with E.Coli Sepsis/ N. Solanki, S. Tackett, C. Clifford, C. Campanaro, K.-K. Horton, D.R. Fletcher, D. Nethery, Y.-H.H. Hsieh, T.L. Bonfield, T. Dick, F. Jacono, Cleveland, OH, p.A1702 P125 Recovery of Immune Homeostasis Via AMPK Activation in Spite of Parkin-Deficiency in Mice with Sepsis-Induced Immunosuppression/ J. Zmijewski, N.B. Bone, E.J. Becker, M. Husain, S. Jiang, B. Chacko, J.-M. Tadie, V. Daley-Usmar, V.J. Thannickal, Birmingham, AL, p.A1703 P126 PPAR-Gamma Agonism Can Alleviate the Hyperimmune Response in Pediatric Sepsis/ I. Koutroulis, C.E. Hoptay, R.J. Freishtat, Washington, DC, p.A1704 P127 Characterization of Microparticle Gasdermin-D in Patients in the Medical Intensive Care Unit/ E. Homsy, P. Consiglio, S. Das, H. Nagaraja, M.D. Wewers, M.C. Exline, A. Sarkar, Columbus, OH, p.A1705 P128 VEGF-121 Therapy Mitigates Halogen Inhalation-Induced Injury in Pregnant Mice/ J.A. Lambert, W.E. Bradley, L. Dell’Italia, S. Doran, S. Aggarwal, N. Ambalavanan, R.P. Patel, T. Jilling, S. Matalon, Birmingham, AL, p.A1706 P129 Airway Epithelial Hepcidin Coordinates Pulmonary Macrophage and Local Iron Against Bacterial Pneumonia/ Q. Chen, Y. Yang, C. Zeng, S. Yang, S. Song, S. Liu, X. Fang, Q. Shu, Hangzhou, China, p.A7311 CLINICAL THEMATIC POSTER SESSION A46 CRITICAL CARE CASE REPORTS: ACID BASE, ELECTROLYTES, ENDOCRINE, METABOLIC AND RENAL 9:15 a.m. - 4:15 p.m. KBHCCD Area G (Hall F, Level 2) Viewing: Posters will be on display for entire session. Discussion: 11:15-12:00: authors will be present for individual discussion 12:00-1:00: authors will be present for discussion with assigned facilitators. Facilitators : C.M. Hendrickson, MD, MPH, San Francisco, CA P. Bhatraju, MD, Seattle, WA P937 Nivolumab-Induced Hypophysitis/ M. Reaven, W. Bender, C. Swenson, Atlanta, GA, p.A1707 P938 Therapeutic Plasma Exchange for Acute Thyroid Storm in the Setting of Methamphetamine-Induced Gut Ischemia and Shock/ J.S. Lee, K. Seng, K.A. Welch, A.C. Chan, I.E. Brown, A.M. Semrand, A.A. Zeki, Sacramento, CA, p.A1708 P939 Not Your Textbook Thyroid Storm: Paradoxical Beta Blocker Decompensation Masking Unusual Cardiac Manifestations/ A. Ramaniuk, Columbus, OH, p.A1709 P940 A Case of Thyroid Storm with Ventricular Fibrillation Arrest/ N. Jiwa, Waterbury, CT, p.A1710 P941 SubClinical Hypothyroidism with Myxedema Symptoms/ R. Russo, E. Brume, A. Shawkat, R. Dean, Syracuse, NY, p.A1711 P942 Thyroid Storm Presenting with Multiorgan Failure and Severe Lactic Acidosis/ J.D. Price, K. El-Kersh, Louisville, KY, p.A1712 P943 In the “I” of the Storm: Thyroid Storm Induced by Iodine Contrast in Thyrotoxicosis/ M. Kauth, A. Sheikh, L. Hinkle, Indianapolis, IN, p.A1713 P944 ROSC with Methylprednisolone: A Case of Cardiac Arrest Due to Myxedema/ H. Yousaf, C. Allen, D. Roma, Savannah, GA, p.A1714 P945 The Domino(Side) Effect: Steroid Induced Ketosis Post Rapid Sequence Intubation with Etomidate and Hydrocortisone/ A. Alexis, Miami, FL, p.A1715 P946 Early Use of Continuous Renal Replacement Therapy (CRRT) for Septic Shock in an End-Stage Renal Disease (ESRD) Patient/ H.-I. Liao, K.A. Radigan, Chicago, IL, p.A1716 P947 Transcontinental Dialysis at 30,000 Feet/ S. Diffley, T.C. Ross, D.J. Pearson, Dayton, OH, p.A1717 P948 The Critically Ill Patient with a Renal Transplant/ I. Bronshteyn, S.M. Pastores, N. Halpern, New York, NY, p.A1718 Facilitators : S. Beesley, MD, MSc, Salt Lake City, UT P. Shah, MD, Gainesville, FL P949 Metformin Associated Lactic Acidosis and Acute Renal Failure: A Case Report/ Y. Eslaamizaad, A. Mehta, B.W. Fouty, P. Almalouf, Mobile, AL, p.A1719 ATS 2019 • Dallas, TX SUNDAY • MAY 19 63 SUNDAY MORNING

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