ATS 2019 Virtual Final Program

P676 Investigation of Clinical Factors Corelated with Airway Tissue Eosinophils/ K. Chibana, Y. Horigane, N. Uchida, M. Masawa, R. Koike, Y. Nakamura, T. Watanabe, T. Shiobara, R. Arai, Y. Shimizu, A. Takemasa, Y. Ishii, Mibu Tochigi, Japan, p.A1288 P677 Mannose-Binding Lectin Plasma Concentration and MBL Gene Rs1800450 Polymorphism in Asthmatics Children/ S. Tereshchenko, M. Smolnikova, N. Gorbacheva, E. Anisimova, Krasnoyarsk, Russian Federation, p.A1289 P678 Prevalence and Utility of Spirometry in Developing a Retrospective Asthma Cohort at an Academic Pulmonary Clinic/ U. Shrestha, M. Saul, M.L. Fajt, M. Gauthier, Pittsburgh, PA, p.A1290 P679 Impact of Sinus Surgery on Th2-Mediated Airway and Systemic Inflammation in Asthma/ K. Hamada, K. Oishi, K. Matsuda, S. Uehara, R. Suetake, M. Asami, Y. Yamaji, N. Edakuni, T. Hirano, K. Matsunaga, Yamaguchi, Ube, Japan, p.A1291 P680 Optimising the Discovery of Breath-Based Biomarkers for Phenotyping Acute Exacerbations of Asthma and COPD/ M. Wilde, R. Cordell, M. Richardson, W. Ibrahim, B. Zhao, D. Salman, L. Bryant, R. Free, A. Singapuri, N. Greening, P. Thomas, C. Brightling, P. Monks, S. Siddiqui, Leicester, United Kingdom, p.A1292 Facilitator : M.L. Curtiss, MD, PhD, Birmingham, AL P681 Small Airways Disease Parameters Defined by PExA Particle Mass in Asthma, Asthma Remission and Healthy Controls/ O. Carpaij, S. Brouwer, H.A.M. Kerstjens, A.-C. Olin, M.C. Nawijn, M. van den Berge, Groningen, Netherlands, p.A1293 P682 Exacerbation Rate Reduction According to Baseline Blood Eosinophilic Count in Patients with Asthma Treated with ICS/LABA Maintenance and Reliever Therapy/ G.G. Brusselle, A. Papi, G. Nicolini, L. Santoro, D. Guastalla, Ghent, Belgium, p.A1294 P683 Neutrophil Elastase and Eosinophil Derived Neurotoxin in Sputum from Elderly Patients with Asthma/ T. Soma, Y. Uchida, T. Kobayashi, K. Nakagome, M. Nagata, Saitama, Japan, p.A1295 P684 Fractional Exhaled Nitric Oxide and Peripheral Blood Eosinophil Count Prognostic and Predictive Biomarkers in Severe Eosinophilic Asthma/ R. Shrimanker, R. Price, S.E. Wenzel, S. Yancey, I. Pavord, Oxford, United Kingdom, p.A1296 P685 Clinical Relevance of Capsaicin Cough Sensitivity to Uncontrolled Asthma/ Y. Kanemitsu, K. Fukumitsu, N. Takeda, R. Kurokawa, K. Ito, H. Nishiyama, S. Yamamoto, Y. Inoue, S. Fukuda, O. Takakuwa, H. Ohkubo, K. Maeno, Y. Ito, T. Oguri, M. Takemura, A. Niimi, Nagoya, Japan, p.A1297 P686 An Investigation of Geographic Influence on CompEx, a Surrogate Endpoint for Severe Asthma Exacerbations/ A.L. Fuhlbrigge, T.W. Harrison, M. Fagerås, A. Jauhiainen, L.E.J.M. Scheepers, J. Zangrilli, C.A. Da Silva, Denver, CO, p.A1298 P687 To Study the Role of T H 17 and T Regulatory Cells in Developing Asthma in a Birth Cohort of Babies/ A. Agarwal, M. Singh, M. Singh, Chandigarh, India, p.A1299 P688 ADRB2 Polymorphism and Altered Response to Long Acting Beta Agonists (LABA) Therapy in North Indian Children with Asthma/ M. Kumar, A. Chauhan, M. Singh, Chandigarh, India, p.A1300 P689 Childhood Measles Is Associated with Lower Risk of Adult Atopic Asthma but Only Among Those Who Had Childhood Eczema/ J.L. Perret, C.J. Lodge, A.J. Lowe, C. Svanes, S.C. Morrison, G. Bowatte, D.S. Bui, G. Hamilton, B. Thompson, I.H. Feather, P.S. Thomas, M.J. Abramson, E.H. Walters, S.C. Dharmage, Melbourne, Australia, p.A1301 P690 Lower Airway Microbiota Associates with Inflammatory Phenotype in Severe Preschool Wheeze/ P.F.M. Robinson, C. Pattaroni, J. Cook, L. Gregory, A. Martin Alonso, L. Fleming, C. Lloyd, A. Bush, B.J. Marsland, S. Saglani, London, United Kingdom, p.A1302 P691 Nasal Microbiome Dysbiotic and Frequent Exacerbations in Asthma Patients/ M. Xie, Wuhan, China, p.A1303 P692 Asthma Sub-Phenotyping in Plasma from U-BIOPRED and BIOAIR Using Array-Based Proteomics/ M. Mikus, J. Kolmert, L.I. Andersson, A. James, C. Gomez, B.U. Dahlen, B. De Meulder, R. Djukanovic, P.J. Sterk, I.M. Adcock, P. Nilsson, S.E.K. Dahlen, Stockholm, Sweden, p.A7306 P693 A Predictive Model for Clinical Asthma Exacerbations Using Albuterol eMDPI (ProAir Digihaler): A 12-Week, Open-Label Study/ G. Safioti, L. Granovsky, T. Li, M. Reich, S. Cohen, Y. Hadar, R. Pleasants, T. Hill, M. DePietro, Amsterdam, Netherlands, p.A7307 CLINICAL • TRANSLATIONAL THEMATIC POSTER SESSION A32 ASTHMA: CLINICAL STUDIES II 9:15 a.m. - 4:15 p.m. KBHCCD Area E (Hall F, Level 2) Viewing: Posters will be on display for entire session. Discussion: 11:15-12:00: authors will be present for individual discussion 12:00-1:00: authors will be present for discussion with assigned facilitators. Facilitator : M. Gauthier, MD, Pittsburgh, PA P695 Efficacy of Omalizumab in Reducing Asthma Exacerbation in Asian Patients: A Pooled Analysis of Two Randomized Placebo-Controlled Studies/ M. Huang, J. Li, S. Liu, N. Zhong, J. Yang, L. Wang, K. Sumi, X.H. Lau, R.B. Fogel, X. Jaumont, GuangZhou, China, p.A1304 P696 Self-Administration of Mepolizumab Liquid Using a Single-Use Prefilled Autoinjector/ K.R. Chapman, D. Bernstein, I.D. Pavord, R. Follows, J.H. Bentley, I. Pouliquen, E.S. Bradford, Toronto, Canada, p.A1305 P697 Self-Administration of Mepolizumab Liquid Using a Single-Use Prefilled Syringe/ E.S. Bradford, D. Bernstein, L. Bjermer, R. Follows, J.H. Bentley, I. Pouliquen, E.H. Bel, Research Triangle Park, NC, p.A1306 P698 Mepolizumab Prefilled Autoinjector and Prefilled Syringe Real World Use: The Patient Experience/ L. Evitt, R. Follows, J.H. Bentley, W. Williams, H. Shalhoub, M. Celone, R. von Maltzahn, Brentford, United Kingdom, p.A1307 ATS 2019 • Dallas, TX 46 SUNDAY • MAY 19