ATS 2019 Virtual Final Program

12:27 American Lung Association D.P. Brown, BS, MS, CHES, Washington, DC 12:39 National Institute of Nursing Research K. Huss, PhD, Bethesda, MD 12:51 National Heart, Lung, and Blood Institute L. Reineck, MD, Bethesda, MD 1:03 Panel Discussion J.L. Guttormson, PhD, RN, Milwaukee, WI DIVISION OF LUNG DISEASES, NHLBI/NIH L24 COMMUNITY BASED INTERVENTIONS IN NHLBI’S ASTHMA EMPOWERMENT COLLABORATIONS TO REDUCE CHILDHOOD ASTHMA DISPARITIES 12:15 p.m. - 1:15 p.m. KBHCCD Room D167/D174 (Level 1) Target Audience Care providers for children with asthma, investigators interested in community based research and investigators interested in how to implement evidence-based interventions in the community Objectives At the conclusion of this session, the participant will be able to: • understand how to integrate asthma care from multiple providers; • learn about adapting an intervention to meet the needs of a community; • understand how the use of nontraditional health care workers promote asthma care. In 2017, NHLBI funded cooperative agreements to conduct clinical trials in the Asthma Empowerment Collaborations to Reduce Childhood Asthma Disparities program. Four asthma care implementation programs were funded to provide and assess multilevel (medical care, home, family, and environment) interventions tailored to the needs of the specific communities in which they are delivered. The evidence based interventions in the 4 independent clinical trials will be discussed, focusing on the considerations to implement the interventions in specific contexts. The types of interventions that will be discussed include school based programs, the use of community health workers, and home based evaluations. Chairing: M.M. Freemer, MD, MPH, Bethesda, MD 12:15 School Based Asthma Interventions in the Asthma Empowerment Program A.A. Lowe, BS, Tucson, AZ 12:30 Community Health Workers and Pediatric Asthma Care in the Asthma Empowerment Program T. Bryant-Stephens, MD, Philadelphia, PA 12:45 Use of Home Visits/Evaluations in Asthma Care in the Asthma Empowerment Program R.S. Everhart, PhD, Richmond, VA 1:00 Panel Discussion DIVISION OF LUNG DISEASES, NHLBI/NIH L25 CLINICAL FINDINGS FROM THE NHLBI PVDOMICS PROGRAM IN PATIENTS WITH PULMONARY HYPERTENSION 12:15 p.m. - 1:15 p.m. KBHCCD Room D221/D225/D226 (Level 2) Target Audience Health providers, trainees, and researchers Objectives At the conclusion of this session, the participant will be able to: • learn about sleep characterization in PH; • learn about new radiomics, genomics, and proteomics findings in PH; • learn about new clinical phenotypes clustering in PH. Pulmonary hypertension (PH) currently has no cure, thus PH research remains a high priority for NHLBI. The currently accepted classification of PH is challenging to apply clinically in the age of precision medicine. In 2014, NHLBI launched a major multi-center clinical study of PH named: Redefining Pulmonary Hypertension through Pulmonary Vascular Disease Phenomics (PVDOMICS). This program includes one Data Coordinating Center (DCC) and six U.S. clinical centers that are conducting an observational study in patients with all types of PH. The overall goal of the PVDOMICS network is to perform comprehensive phenotyping across WHO groups as well as intermediate phenotypes in order to reconstruct the traditional classification and define new meaningful subclassifications. Currently, since the start of enrollment in 2017, there have been over 750 participants with a goal of 1500 by the fall of 2019. This session will describe the clinical results from the study in approximately the first 1000 subjects. Chairing: L. Xiao, MD, PhD, Bethesda, MD N.S. Hill, MD, Boston, MA 12:15 Sleep Disordered Breathing Across Pulmonary Hypertension WHO Groups: Novel Findings from the PVDOMICS Study R. Mehra, MD, Cleveland, OH 12:30 Radiomics in Pulmonary Hypertension: What Have We Learned from PVDOMICS? J. Lempel, MD, Cleveland, OH 12:45 Cluster Analysis of Pulmonary Hypertension Patients in PVDOMICS Using Extensive Multi-Layered Clinical Phenotypes J. Barnard, PhD, Cleveland, OH 1:00 Novel Proteomics and Genomics Findings in Pulmonary Hypertension Patients from PVDOMICS Study M. Aldred, PhD, Indianapolis, IN ATS 2019 • Dallas, TX 370 WEDNESDAY • MAY 22