ATS 2019 Virtual Final Program

BASIC • TRANSLATIONAL MINI SYMPOSIUM C98 HOST RESPONSE TO LUNG INFECTIONS: INSIGHTS INTO NEW MECHANISMS 2:15 p.m. - 4:15 p.m. KBHCCD Ballroom A Two (Level 2) Chairing: S.E. Evans, MD, Houston, TX J.C. Deng, MS, MD, Ann Arbor, MI H. Koziel, MD, Boston, MA Oral Presentations 2:15 Dynamic Alveolar Macrophages Responses to Pneumococcal Pneumonia/ E.I. Arafa, A.T. Shenoy, A. Guillon, I.M.C. Martin, K. Barker, C. Lyon De Ana, A.K. Wooten, M.R. Jones, L.J. Quinton, J.P. Mizgerd, Boston, MA, p.A5593 2:30 NLRP10 Regulates IL-17A/G-CSF Axis to Dampen Pulmonary Host Defense in MRSA Pneumonia/ S. Paudel, L. Ghimire, L. Jin, S. Cai, S. Jeyaseelan, Baton Rouge, LA, p.A5594 2:45 Streptococcus Pneumoniae Pneumonia Induces Mitochondrial Biogenesis and Antioxidant Responses in Mice/ A.J. Losier, L.K. Sharma, Y. Zhang, W. Liu, P. Lee, C. Dela Cruz, New Haven, CT, p.A5595 3:00 Induction of Lower Airway Dysbiosis with Oral Commensals Leads to a Time-Dependent and Persistent Th17 Inflammatory Profile in the Lower Airways of Mice Independent of Cage Effect/ B. Franca, B. Wu, J. Tsay, L. Perez, Y. Li, E. Olsen, I. Sulaiman, A. Gonzalez, K. Yie, S. Ma, A.-M. Zavitsanou, E. Ivanova, S.B. Koralov, L.N. Segal, New York, NY, p.A5596 3:15 Synergistic Gene and Protein Expression Analyses Reveal Roles of NFkB and JUN in Inducible Epithelial Resistance Against Infection/ J. Pantaleon-Garcia, V. Kulkarni, Y. Wang, S.E. Evans, Houston, TX, p.A5597 3:30 Eosinophils and Macrophages Direct Allergic Host Responses During Synergistic Viral-Bacterial Infections/ A.E. Samarasinghe, K. LeMessurier, M. Tiwary, H. Smallwood, Memphis, TN, p.A5598 3:45 Interferon Lambda Inhibits Bacterial Clearance During Influenza, MRSA Super-infection/ H. Rich, C. McCourt, W.Q. Zheng, K. McHugh, Pittsburgh, PA, p.A5599 4:00 The Development of Klebsiella Pneumoniae Vaccine Strategy via Eliciting the Serotype-Independent Immunity in the Lung/ N. Iwanaga, I. Sandquist, K. Chen, E. Norton, J. Moreno, J.K. Kolls, New Orleans, LA, p.A5600 BASIC • CLINICAL • TRANSLATIONAL MINI SYMPOSIUM C99 SRN: CARDIOMETABOLIC CONSEQUENCES OF SLEEP DISORDERED BREATHING AND THE ROLE OF CPAP THERAPY 2:15 p.m. - 4:15 p.m. KBHCCD Room D167/D174 (Level 1) Chairing: E. Tasali, MD, Chicago, IL N.M. Punjabi, MD, PhD, Baltimore, MD S.S. Redline, MD, MPH, Boston, MA Oral Presentations 2:15 Effect of Continuous Positive Airway Pressure Treatment in Untreated Hypertensive Patients Depending on the Circadian Blood Pressure Pattern/ E. Sapina-Beltran, G. Torres, I. Benitez, F. Santamaria-Martos, J. Duran-cantolla, M. Sanchez-de-la-torre, F. Barbe, M. Dalmases, Lerida, Spain, p.A5601 2:30 Maternal Sleep-Disordered Breathing in Pregnancy Increases Nocturnal Glucose Levels in Women with Gestational Diabetes/ R. Newbold, S. Meltzer, A. Benedetti, N. Garfield, E. Rey, L. Lavigne, A. Olha, K. Dasgupta, R. Gagnon, R.J. Kimoff, S. Pamidi, Montreal, Canada, p.A5602 2:45 Effect of CPAP on Circulating Exosomal MicroRNAs in Patients with Morbid Obesity and Obstructive Sleep Apnea (OSA)/ D. Sanz Rubio, L. Pastor, J. Lazaro, I. Martin-Burriel, J.M. Marin, Zaragoza, Spain, p.A5603 3:00 Lower Oxygen Saturation During Sleep Is Associated with Reduced Expressions of CD1D and RAB20 That Is Potentially Reversed by CPAP Therapy/ R. Li, R. Joehanes, H. Lin, A. Gower, B.E. Cade, J. Li, S. Williams, H. Wang, N.M. Punjabi, R. Mehra, S.R. Patel, S.F. Quan, Y. Liu, S.A. Gharib, J. Rotter, S. Rich, D. Levy, A. Spira, S.S. Redline, D.J. Gottlieb, T. Sofer, Boston, MA, p.A5604 3:15 Associations of Sleep Disordered Breathing and Insomnia with Incident Hypertension and Diabetes: A Prospective Analysis of Data from the Hispanic Community Health Study/Study of Latinos/ X. Li, D. Sotres-Alvarez, T. Sofer, L.C. Gallo, L. Aviles-Santa, K.M. Perreira, C.R. Isasi, A.R. Ramos, P.C. Zee, K.L. Savin, N. Schneiderman, S. Smoller, M. Daviglus, S. Redline, Boston, MA, p.A5605 3:30 Insufficient Sleep Impairs Vascular Health in Women/ R. Shah, M. Emin, R. Sampogna, B. Aggarwal, M. St-Onge, Y. Wei, S. Jelic, New York, NY, p.A5606 3:45 Effect of Sleep Apnea and Its Treatment in the Prognosis of Patients with Acute Coronary Syndrome: Isaacc Study/ M. Sanchez De La Torre, A. Sánchez-de-la-Torre, S. Bertran, J. Abad, J. Duran-Cantolla, V. Cabriada, O. Mediano, M.J. Masdeu, M.L. Alonso, J.F. Masa, M. de-la-Peña, M. Mayos, R. Coloma, J.M. Montserrat, E. Chiner, S. Perelló, G. Rubinós, O. Mínguez, change L. Pa, to L. Pascual, A., A. Cortijo, D. Mart`inez, A. Aldom`a, D. McEvoy, F. Barbe, Lleida, Spain, p.A5607 ATS 2019 • Dallas, TX TUESDAY • MAY 21 299 TUESDAY AFTERNOON