ATS 2019 Virtual Final Program

P112 Modelling Virus-Host Interactions: TLR-Induced Release of Inflammatory Mediators in Human Lung Explants/ D. Thakker, A.P. Henry, C.K. Billington, B. Kc, I. Sayers, I.P. Hall, Nottingham, United Kingdom, p.A5213 P113 Nasal Wash Cytokine Concentrations in Pediatric Allogeneic Hematopoietic Cell Transplant Recipients with Respiratory Viral Infections/ T. Flerlage, A. Souquette, E.K. Allen, J. Wolf, G. Maron, P.G. Thomas, Memphis, TN, p.A5214 P114 Multicenter Survey of Respiratory Complications After Influenza in the Season Between 2017 and 2018 in Tokyo Central Area: Final Report/ N. Nishimura, R. Imai, M. Nakamura, Y. Suzuki, T. Mochizuki, Tokyo, Japan, p.A5215 P115 Seasonality and Virus Transmission/ S.S. Thompson, C. Sloan, Provo, UT, p.A5216 Facilitator : R. Menendez, MD, Valencia, Spain P116 The Impact of Heart Failure on Influenza Pneumonia Outcomes/ A. Karki, R. Reddy, I. Asante, L. Riley, C.A. Trillo, Gainesville, FL, p.A5217 P117 Understanding the Viral and Host Factors That Influence Viral Detection Rates with Nasopharyngeal Swab Compared to Bronchoalveolar Lavage/ E. Alba, K.I. Aronson, L. Sanso, K. Rajwani, New York, NY, p.A5218 P118 Comparative Seasonal Respiratory Virus Epidemic Timing in Utah/ Z. Callahan, T.K. Smith, C. Ingersoll, R. Gardner, K. Korgenski, C. Sloan, Provo, UT, p.A5219 P119 Viral Pneumonia Studied at University Hospital in Buenos Aires/ M. Carpio, Buenos Aires, Argentina, p.A5220 P120 Asthma, COPD, Respiratory Infections and Viruses: Admission Rates, ER Visits and Age/ R.P. Cusack, I. Satia, N.W. Johnston, J.M. Greene, K.J. Killian, P. O’Byrne, Hamilton, Canada, p.A5221 P121 Comorbidities Associated with Respiratory Viral Infections in Egypt in Non Intensive Care Unit Cases.Single Site Experience/Cairo University Hospitals from 2010 to 2014/ U.E. Aboelhassan, A.M. Hatem, S.M. Abdelwahab, M.S. Abdelwahab, A. Elkholy, Cairo, Egypt, p.A5222 P122 Effect of Anticoagulation on Pulmonary Hemorrhage in Influenza/ W. Bassett, N. Mackman, J.A. Bastarache, Nashville, TN, p.A5223 BASIC • TRANSLATIONAL THEMATIC POSTER SESSION C58 MECHANISMS OF PULMONARY FIBROSIS 9:15 a.m. - 4:15 p.m. KBHCCD Area C (Hall F, Level 2) Viewing: Posters will be on display for entire session. Discussion: 11:15-12:00: authors will be present for individual discussion 12:00-1:00: authors will be present for discussion with assigned facilitators. Facilitator : S.K. Huang, MD, Ann Arbor, MI P265 Calpain Inhibition Decreases Fibroblast Differentiation and Matrix Deposition and Represents a Novel Approach to Treat Lung Fibrosis/ D. Kim, C. Wong, J. Beckett, C. Schaefer, S.R. Lim, R. Rajagopalan, P. Ibrahim, B. Buckman, H. Dietz, M.E. Fuentes, South San Francisco, CA, p.A5224 P266 The Effects of Combined Antifibrotic Therapy in Bleomycin Induced Pulmonary Fibrosis/ E.D. Abston, P. Caravan, M. Lanuti, Boston, MA, p.A5225 P267 The Effect of Nintedanib on Pulmonary Vascular Tone in an Experimental Model of Lung Fibrosis and Pulmonary Hypertension/ N. Chandran, N. Sharma, S.L. Wollin, A. Olschewski, G. Kwapiszewska, H. Olschewski, Graz, Austria, p.A5226 P268 Role of IGF-1R Pathway in Idiopathic Pulmonary Fibrosis/ M.S. Espindola, D.M. Habiel, Y.A.P.J. Sá, M. Hohmann, I.C. Jones, A.L. Coelho, C.M. Hogaboam, Los Angeles, CA, p.A5227 P269 Spermidine Attenuated Bleomycin Induced Lung Injury/Fibrosis by Inhibition of Endoplasmic Reticulum Stress (ers) Induced Apoptosis and Cellular Senescence/ S.-W. Park, M. Kim, A.-R. Baek, J.H. Lee, A.-S. Jang, D. Kim, Bucheon, Korea, Republic of, p.A5228 P270 Extracellular Heat Shock Protein 90 a Mediates Cellular Senescence in Pulmonary Fibrosis/ H. Dong, W. Zhong, C. Ye, J. Zhang, X. Wan, S. Cai, Guangzhou, China, p.A5229 P271 Differential Expression of Caveolin-1 Modulates Lung Parenchymal Remodeling Leading to Combined Pulmonary Fibrosis and Emphysema: Effect of Phosphodiesterase -5 Inhibitor/ R. Kulshrestha, H. Singh, A. Pandey, S. Bharadwaj, K. Ravi, Delhi, India, p.A5230 P272 The Importance of Multiple-Site Sampling in Understanding the Pathogenesis of Idiopathic Pulmonary Fibrosis/ J. Fukumoto, S. Patil, M. Alleyn, S. Krishnamurthy, L. Galam, K. Patel, R. Hooker, J. Dunning, R.F. Lockey, N. Sharma, N. Kolliputi, Tampa, FL, p.A5231 Facilitator : A. McCubbrey, PhD, Denver, CO P273 Role of HMSG2 Mediated FAO Deficiency in IPF Pathogenesis/ G. Yu, J. Yang, W. Zhao, X. Guo, Xinxiang, China, p.A5232 P274 Galectin-3 Plasma Levels and Secretion Mechanism in Idiopathic Pulmonary Fibrosis/ G. Shaughnessy, A. Egan, H. Dasari, M. Ali, V. Van Kuelen, T. Peikert, E.M. Carmona Porquera, Rochester, MN, p.A5233 P275 TRIM72 Is an Injury-Response Gene in the Lung That Ameliorates Bleomycin-Induced Pulmonary Fibrosis Through Multifaceted Mechanisms/ X. Cong, N. Nagre, A.C. Pearson, J. Herrera, H. Ji, D. Jiang, P.B. Bitterman, R.D. Hubmayr, X. Zhao, Norfolk, VA, p.A5234 P276 Exploration of Novel Biomarkers of Fibrosis by Proteomics of Exosomes/ T. Matsuki, T. Koba, T. Takimoto, Y. Takeda, A. Kumanogoh, H. Kida, Suita-Shi, Japan, p.A5235 ATS 2019 • Dallas, TX TUESDAY • MAY 21 271 TUESDAY MORNING