ATS 2019 Virtual Final Program

P211 Early to Pressors, Early to Leave Against Medical Advice - Cotton Fever in IV Drug User/ P. Chandrika, J. Hussain, S. Ghadermarzi, M.R. Bowling, Greenville, NC, p.A4854 P212 A 60 Year Old Female with Rheumatoid Arthritis and Psoriatic Arthritis Presents with New Onset Pancytopenia and Coffee Ground Emesis/ V. Kuppuswamy, J.A. Haspel, St. Louis, MO, p.A4855 BEHAVIORAL THEMATIC POSTER SESSION C43 COPD AND POPULATION HEALTH 9:15 a.m. - 4:15 p.m. KBHCCD Area F (Hall F, Level 2) Viewing: Posters will be on display for entire session. Discussion: 11:15-12:00: authors will be present for individual discussion 12:00-1:00: authors will be present for discussion with assigned facilitators. Facilitator : M.B. Rice, MD, MPH, Boston, MA P849 The Obesity Paradox in COPD Is Absent in U.S. Never-Smokers/ T.D. Wu, M.C. McCormack, R.A. Wise, E. Brigham, Baltimore, MD, p.A4856 P850 Epigenetic Clock Perturbations May Link Development and Aging with Lung Disease in Women/ P. Kachroo, J. Morrow, S.J. Leeder, C.A. Vyhlidal, R. Gaedigk, E.K. Silverman, S.T. Weiss, K.G. Tantisira, D.L. DeMeo, Boston, MA, p.A4857 P851 Pathogenic Primary Ciliary Dyskinesia Pathway Variants Associate with Disease Severity in At-Risk Smokers and COPD Subjects from SPIROMICS/ C.E. Brehm, F. Genese, C.R. Marion, X. Li, W.K. O’Neal, J.D. Newell, G.A. Hawkins, R.G. Barr, C.B. Cooper, D. Couper, M.K. Han, N.N. Hansel, R.E. Kanner, E.C. Kleerup, F.J. Martinez, R. Paine, P. Woodruff, S.P. Peters, E.A. Hoffman, E.R. Bleecker, D.A. Meyers, V.E. Ortega, Winston-Salem, NC , p.A4858 P852 The Contribution of Individual and Neighborhood Factors to Racial Differences in COPD-Related Health Outcomes in SPIROMICS/ C.O. Ejike, H. Woo, P. Galiatsatos, L.M. Paulin, M.R. Jones, J.A. Krishnan, C.B. Cooper, R.E. Kanner, R.P. Bowler, E.A. Hoffman, A.P. Comellas, G.J. Criner, R.G. Barr, F.J. Martinez, M.K. Han, C. Martinez, V.E. Ortega, T. Parekh, S. Christenson, S. Ragu, A.J. Gassett, J.D. Kaufman, N. Putcha, N.N. Hansel, Baltimore, MD, p.A4859 P853 Residential Segregation and COPD-Related Health Outcomes in SPIROMICS/ H. Woo, P. Galiatsatos, C.O. Ejike, L.M. Paulin, M. Jones, J.A. Krishnan, C.B. Cooper, R.E. Kanner, R.P. Bowler, A.P. Comellas, G.J. Criner, R.G. Barr, F.J. Martinez, M.K. Han, V.E. Ortega, T. Parekh, S. Christenson, S. Raju, A. Gassett, J.D. Kaufman, N. Putcha, N.N. Hansel, Baltimore, MD, p.A4860 P854 Genome-Wide Association Study Identifies Novel Loci and Recapitulates Known Loci for Interstitial Lung Disease in Non-Hispanic Whites from SPIROMICS/ V.E. Ortega, W.K. O’Neal, J.D. Newell, X. Li, G.A. Hawkins, I. Barjaktarevic, R.G. Barr, C.B. Cooper, D. Couper, M.K. Han, N.N. Hansel, R.E. Kanner, E.C. Kleerup, F.J. Martinez, R. Paine, M.B. Scholand, P. Woodruff, S.P. Peters, E.A. Hoffman, D.A. Meyers, E.R. Bleecker, Winston Salem, NC, p.A4861 P855 Genome-Wide Association Study of Acute Exacerbations of COPD Identifies Novel Loci in SPIROMICS/ V.E. Ortega, X. Li, E. Ampleford, W.K. O’Neal, G.A. Hawkins, A. Manichaikul, I. Barjaktarevic, R.G. Barr, C.B. Cooper, D. Couper, M.K. Han, N.N. Hansel, R.E. Kanner, E.C. Kleerup, F.J. Martinez, R. Paine, P. Woodruff, E.A. Hoffman, S.P. Peters, E.R. Bleecker, D.A. Meyers, Winston Salem, NC p.A4862 P856 Rural Residence Is Independently Associated with COPD Prevalence and Morbidity in the National Health and Nutrition Examination Surveys(NHANES)/ S. Raju, L.M. Paulin, N. Putcha, E. Brigham, A. Balasubramanian, M. Maisonet, N.N. Hansel, M.C. McCormack, Baltimore, MD, p.A4863 P857 Lung Function Trajectories Predict Incident Spirometric Abnormalities in Miners/ A. Sood, Y. Tesfaigzi, X.W. Shore, O.B. Myers, H. Petersen, P.M. Meek, N.A. Assad, R. Vazquez Guillamet, W.C. Jarrell, C. Pollard, L. Cook, Albuquerque, NM, p.A4864 P858 Networks of DNA Methylation Loci in Lung Tissue and Peripheral Blood Highlight Cross-Tissue Epigenetic Signatures of COPD/ J. Morrow, K. Glass, P. Sakornsakolpat, M.H. Cho, C.P. Hersh, R. Tal-Singer, R. Bueno, E.K. Silverman, J. Quackenbush, D.L. DeMeo, Boston, MA, p.A4865 Facilitator : D.L. DeMeo, MD, Boston, MA P859 Gene Expression Alterations Associated with Computed Tomography Imaging Clusters of Patients with Chronic Obstructive Pulmonary Disease/ K. Xu, E. Billatos, F. Duan, H. Marques, J. Romanoff, E. Moses, C.S. Stevenson, A. Spira, S. Ash, G.R. Washko, M.E. Lenburg, Boston, MA, p.A4866 P860 Epigenome-Wide Association Study of Pulmonary Function Traits and Chronic Obstructive Pulmonary Disease: A Multiethnic Meta-Analysis/ M.K. Lee, N. Terzikhan, L. Lahousse, M. De Vries, S. Sikdar, S. London, Research Triangle Park, NC, p.A4867 P861 X Chromosome Genetic Associations in COPD/ L.P. Hayden, M.H. Cho, D.A. Lomas, P. Bakke, A. Gulsvik, E.K. Silverman, T.H. Beaty, N. Laird, C. Lange, D.L. DeMeo, Boston, MA, p.A4868 P862 Identification of Biomarkers to Differentiate Asthma and COPD Using RNA-seq Data: A Machine Learning Approach/ S.-Y. Liao, A. Linderholm, K.Y. Yoneda, N.J. Kenyon, R. Harper, Sacramento, CA, p.A4869 P863 Temporal Analysis of Environmental Factors on COPD Admission and Mortality/ J. Carlin, M.K. McGraw, C.M. Henry, C. Boethel, A.C. Arroliga, S.A. Ghamande, Temple, TX, p.A4870 P864 Vitamin B12 Mediated Hyperhomocysteinemia and Adverse Pulmonary Functions: A Population Based Study from Rural North India/ S. Yadav, K. Chandiok, S. Joshi, N. Kiranmala Devi, K.N. Saraswathy, New Delhi, India, p.A4871 ATS 2019 • Dallas, TX TUESDAY • MAY 21 255 TUESDAY MORNING