ATS 2019 Virtual Final Program

617 miR-17~92 Cluster Haploinsufficiency Decreases Pulmonary and Cardiovascular Function Similar to the Phenotype Present in Murine Bronchopulmonary Dysplasia Models/ M.E. Robbins, K.A. Smith, E.M. Mendralla, J.M. Taylor, G.S. Budinger, Chicago, IL, p.A4447 618 Type 2 Cell Low Density Lipoprotein Receptor Related Protein 1 (LRP1) Regulates Surfactant Homeostasis/ C. Agudelo, S. Mendizuri, E. Area-Gomez, Y. Xu, P. Geraghty, I.J. Goldberg, R.F. Foronjy, I. Garcia-Arcos, Brooklyn, NY, p.A4448 619 Stat3 Is Critical for Alveolar Epithelial Regeneration/ A.J. Paris, K.E. Hayer, S.A. Toulmin, D.C. Avgousti, J.A. Zepp, W.J. Zacharias, N. Dai, P. Wang, E.E. Morrisey, M.D. Weitzman, G.S. Worthen, Philadelphia, PA, p.A7390 620 Single Cell Studies Identifies Novel Glial Cell Markers Associated with Distinct Cell Morphology at Lung Neurosensory Structures/ C.S. Kuo, A. Walker, S. Darmanis, Palo Alto, CA, p.A7391 BASIC • TRANSLATIONAL RAPID: RAPID ABSTRACT POSTER DISCUSSION SESSION C29 SRN: FUNDAMENTALS IN SLEEP AND RESPIRATORY NEUROBIOLOGY 9:15 a.m. - 11:15 a.m. KBHCCD Ballroom D Four (Level 3) Abstract Summaries 9:15-9:45 Viewing/Discussion 9:45-11:15 Chairing: Y. Peker, MD, PhD, Istanbul, Turkey M.S. Badr, MD, Detroit, MI M. Macrea, MD, Salem, VA 701 Utility of microRNAs for Obstructive Sleep Apnea Identification/ F. Santamaria-Martos, I. Benitez, C. Giron, A. Zapater, L. Pinilla, J.M. Fernandez-Real, F. Barbe, F. Ortega, M. Sanchez-de-la-Torre, Lleida, Spain, p.A4449 702 The Impact of Obstructive Sleep Apnea on Metabolic Impairments in Non-Obese and Obese Subjects/ M. Ueyama, H. Kokuto, H. Sugihara, S. Oikawa, T. Iizuka, F. Suzuki, K. Ohta, S. Kudoh, Tokyo, Japan, p.A4450 703 Leptin Receptor Positive Neurons in the Dorsomedial Hypothalamus Maintain Upper Airway Patency During Sleep/ H. Pho, Y. Berger, C. Freire, O. Dergacheva, T.A. Fleury Curado, A.R. Schwartz, D. Mendelowitz, V.Y. Polotsky, Baltimore, MD, p.A4451 704 Impact of CPAP Treatment on Leptin and Adiponectin in Coronary Artery Disease and Nonsleepy Obstructive Sleep Apnea - A Secondary Analysis of the RICCADSA Trial/ Y. Peker, B. Balcan, T. Yucel-Lindberg, K. Lindberg, E. Thunström, Istanbul, Turkey, p.A4452 705 Nitric Oxide Inhibits Endothelial Cell Senescence in Human Microvascular Endothelial Cell Culture/ M. Macrea, T.J. Martin, A. Malhotra, Z. Jia, Salem, VA, p.A4453 706 Differential Effects Sustained Vs. Intermittent Hypoxia During Sleep on Pathways of Inflammation, HIF1-Driven Gene Expression and Oxidant Injury/ K. Sundar, J. Song, A.B. DePaula-Silva, T. Wuren, K.A. Sanders, R.S. Fujinami, J.T. Prchal, J.R. Hoidal, Salt Lake City, UT, p.A4454 707 Chronic Intermittent Hypoxia Activates Cardiac Stress-Responsive Mechanisms in a Murine Model of Sleep Apnea: Cardioprotective Effect Influenced by Age/ A.L. Castro-Grattoni, M.C. Suarez-Giron, I. Benitez, L. Pinilla, L. Tecchia, F. Santamaria-Martos, I. Almendros, R. Farre, J.M. Montserrat, D. Gozal, F.E. Barbe, M. Sanchez De La Torre, Lleida, Spain, p.A4455 708 Chronic Intermittent Hypoxia Causes Hepatic Mitochrondial Dysfunction in a Mouse Model of Nonalcoholic Fatty Liver Disease/ O. Mesarwi, P. Wegbrans Giró, A. Lucas, E. Moya Cespedes, F. Powell, E. Breen, A. Malhotra, La Jolla, CA, p.A4456 709 Long-Term Facilitation Following Acute Intermittent Hypoxia Is Present in People with Cervical Spinal Cord Injury During Non-REM Sleep/ S. Vaughan, A. Sankari, S. Carroll, E. Kruppe, A. Salloum, M.S. Badr, Detroit, MI, p.A4457 710 Unilateral Cervical Vagotomy in Mice Undergoing Resistive Breathing Upregulates the Pattern of Breathing Responses to Hypercapnic and Hypoxic Stimuli/ F. Perlikos, I. Koutsourelakis, M. Dettoraki, A. Sotiriou, C.E. Giannakopoulou, T. Vassilakopoulos, Athens, Greece, p.A4458 711 Obstructive Sleep Apnea Does Not Increase Risk of Venous Thromboembolism/ A. Rathore, M.V. Genuardi, R.P. Ogilvie, J.W. Magnani, S.R. Patel, McKeesport, PA, p.A4459 712 Sleep Apnea Severity, Myocardial Infarct Size on Magnetic Resonance Imaging and Coronary Collaterals in ST-Elevation Myocardial Infarction: A Multidisciplinary Study/ N.A. Shah, J. Rowland, S. Khan, A. Kini, M. Menegus, Y. Vengrenyuk, N. Okamoto, H. Ueda, U. Gidwani, J. Kizer, S.S. Redline, R. Kaplan, New York, NY, p.A4460 713 Effect of Continuous Positive Airway Pressure Treatment on Systemic and Ocular Inflammatory Cytokines in Patients with Obstructive Sleep Apnea and Lax Eyelid Syndrome/ J.L. Sanchez, S. Kumar, B. Karcher, O. Iqbal, C. Bouchard, Maywood, IL, p.A4461 714 Measuring Carotid Plaque Inflammation in Moderate to Severe Sleep Apnea Using Hybrid Positron Emission Tomography/Magnetic Resonance Imaging (PET/MRI)/ V. Kundel, A. Sahota, Z. Fayad, V. Mani, N.A. Shah, New York, NY, p.A4462 715 Evaluation of Cardiac Structure and Function Using Cardiac Magnetic Resonance in Co-Existent COPD and OSA/ R. Jen, J. Wilson, D. Wong, F. Contijoch, R.L. Owens, A. Malhotra, Vancouver, Canada, p.A4463 716 Predictive Value of N-Terminal Pro-Brain Natriuretic Peptide for Obstructive Sleep Apnea in Patients with Coronary Artery Disease/ Z. Huang, L. Wang, Y. Liu, K. Huang, Y. Xu, G. Li, J. Luo, J. Chen, Guangzhou, China, p.A4464 717 Obstructive Sleep Apnea: Correlation of Brain Natriuretic Peptide Levels with Cardiovascular Diseases/ N. Uzma, A. Hasan, C. Narasimhan, V.D. Reddy, Hyderabad, India, p.A4465 ATS 2019 • Dallas, TX 238 TUESDAY • MAY 21