ATS 2019 Virtual Final Program

P64 Incidental Non-Cardiac Abnormalities Found on Cardiac CT for Coronary Calcium Scoring/ J.F. Turner, J. Peeke, S. Baveja, J. Crook, T.M. Dudney, Knoxville, TN, p.A3932 P65 Unexpected Metachronous Malignant Melanoma Concurrent and Intermixed Within Primary Non-Small Cell Lung Cancer Tumor/ A. Kozlova, J.B. Gleason, S. Marein, Dayton, OH, p.A3933 CLINICAL THEMATIC POSTER SESSION B68 ONCOGENIC MUTATIONS, METASTASIS, AND NOVEL THERAPEUTICS 9:15 a.m. - 4:15 p.m. KBHCCD Area A (Hall F, Level 2) Viewing: Posters will be on display for entire session. Discussion: 11:15-12:00: authors will be present for individual discussion 12:00-1:00: authors will be present for discussion with assigned facilitators. Facilitator : P.P. Massion, MD, Nashville, TN P67 TRAP1 Downregulation Could Overcome Gefitinib Resistance in NSCLC Via EMT Reversal/ P. Chul, J.W. Jung, K. Hwang, E. Jeong, H.-R. Kim, Iksan, Korea, Republic of, p.A3934 P68 Clinical Significance of Sequential Treatment with Afatinib in the Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor (TKI) Treatment of Patients with EGFR-Mutant Non-Small Cell Lung Cancer (NSCLC)/ N. Kobayashi, H. Aiko, C. Kamimaki, N. Mikami, S. Kubo, Y. Tei, N. Hirama, S. Katakura, S. Teranishi, S. Manabe, M. Yamamoto, M. Kudo, T. Kaneko, Yokohama, Japan, p.A3935 P69 Relationship Between Severity of Adverse Events of Afatinib and Its Pharmacokinetics and Pharmacogenomics for EGFR Mutation-Positive Non-Small Cell Lung Cancer/ T. Gomyo, H. Iihara, H. Hayashi , J. Endo, F. Ito, K. Yansase , D. Kaito, Y. Sasaki, C. Sakai, Y. Fukuda, C. Hirose, T. Sugiyama, A. Suzuki, Y. Ohno, Gifu, Japan, p.A3936 P70 Sequential Anaplastic Lymphoma Kinase (ALK) Inhibitor Prolongs Overall Survival in Patients with ALK-Fusion Advanced Non-Small-Cell Lung Cancer/ A.C.C. Huang, M.C. Ko, C.-H.S. Kuo, Tapei, Taiwan, p.A3937 P71 Elder Patients with Stage IV Lung Adenocarcinoma Harboring Rare EGFR Mutations Treated with a First-Line Tyrosine Kinase Inhibitor Might Have Better Outcome than Younger Patients/ Y.-C. Tsai, C.-J. Yang, M.-J. Tsai, J.-Y. Hung, M.-H. Lee, Y.-M. Tsai, M.-S. Huang, Y.W. Chung, Kaohsiung City, Taiwan, p.A3938 P72 Thoracic Meningioma Metastases: A Single-Center Review/ G. Stroh, T. Peikert, Rochester, MN, p.A3939 P73 Programmed Death Ligand-1 (PD-L1) Expression in Patients with Non-Small Cell Lung Cancer (NSCLC) with Unusual Metastasis: A Case Series/ R. Tsugitomi, N. Nishimura, R. Imai, K. Okafuji, A. Kitamura, Y. Tomishima, T. Jinta, K. Suzuki, T. Tamura, Tokyo, Japan, p.A3940 P74 Altered Exosomal Transcriptome Profile of Lung Cancer with Brain Metastasis/ J. Zhang, Z. Wu, H. Pan, Y. Zhou, L. Chen, S. Tan, S. Li, Guangzhou, China, p.A3941 P75 Lymph Nodes in Lung Cancer Patients with Granulomatous Disease: To Be or Not To Be Metastasis/ S. Baveja, E. Heidel, J.F. Turner, L. Nodit, Knoxville, TN, p.A3942 P76 Significance of Ground Glass Opacities in Patients with Extra-Pulmonary Malignancies/ V. Mehta, D.E. Stover, M.B. Feinstein, New York, NY, p.A3943 P77 Control of Oligo-Metastases Might Allow Cure of Some Patients with Advanced Non-Small Cell Lung Cancer: A Retrospective Single Institutional Analysis/ T. Aoki, S. Tajiri, N. Hayama, N. Okada, K. Enokida, S. Hattori, S. Obayashi, T. Takeuchi, F. Takahashi, G. Takahashi, K. Harada, J. Tanaka, M. Sato, Y. Horio, H. Takiguchi, H. Tomomatsu, K. Tomomatsu, T. Takihara, K. Niimi, T. Oguma, T. Urano, T. Abe, K. Asano, Isehara City, Japan, p.A3944 P78 Pulmonary Delivery of Human IgG Antibody Using a Novel Digital Inhaler in a Rodent Animal Model/ S. Kesten, J. Balarashti, C. Besch-Williford, H. Nelson-Keherly, Boone, NC, p.A3945 Facilitator : S.J. Moghaddam, MD, Houston, TX P79 Immune Response to Percutaneous Cryoablation of Lung Cancer/ K. Gershner, D. Katzman, E. Olsen, A. Winters, J. Alexandre, A. Miller, V. Rao, S. Advani, J. Tsay, W.H. Moore, P. Chattopadhyay, D.H. Sterman, New York, NY, p.A3946 P80 Localized Chemotherapy in Early Stage Lung Cancer Through the Design of a Rocaglate-Eluting Superhydrophobic Polymer Mesh/ J. Lui, J.T. Miller, A.H. Colby, L.E. Brown, J.A. Porco, Jr., Y.L. Colson, M.W. Grinstaff, Boston, MA, p.A3947 P81 Therapeutic Efficacy of Zinc Oxide Nanoparticles Against Small Cell Lung Cancer in an Orthotopic Xenograft Model/ R. Tanino, Y. Amano, X. Tong, R. Sun, J. Umemoto, M. Kobayashi, Y. Shiratsuki, T. Okuno, A. Tanino, M. Nakao, T. Hotta, M. Hamaguchi, T. Okimoto, Y. Tsubata, S. Hamaguchi, N. Kurimoto, H. Takeyama, Y. Fujita, T. Isobe, Izumo, Japan, p.A3948 P82 Enhanced Tumor Regression and Immune Cell Infiltration by Inhaled Submicron Particle Paclitaxel in an Orthotopic Athymic Nude Rat Model of Non-Small Cell Lung Cancer (NSCLC)/ W. Johnston, J. Verco, M. Frost, P. Kuehl, M. Baltezor, G. diZerega, San Luis Obispo, CA, p.A3949 P83 Mistletoe Lectin as Treatment for Small Cell Lung Cancer Expressing Myc Family Oncoproteins/ M.A. Shatat, E. Yuan, R.T. Lee, Cleveland, OH, p.A3950 P84 Complement C5a Facilitates Recruitment of Monocytes Via Chemokine CCL2 Produced by PMCs in Malignant Pleural Effusion/ L. Lisha, X. Li, X. Hu, Q. Gu, P. Deng, W. Tang, S. Deng, C. Hu, J. Feng, Changsha, China, p.A3951 P85 Mitochondrial Drp1 Binding Partners MiD49 and MiD51 Are Epigenetically Upregulated in Lung Cancer: A Novel Mitochondrial-Targeted Approach to Cell Cycle Regulation and Cancer Therapy/ A. Das Gupta, K.-H. Chen, D. Wu, V. Hoskin, J.D. Mewburn, P.D.A. Lima, L.R.G. Parlow, C.C.T. Hindmarch, A. Martin, E.A. Sykes, S.L. Archer, Kingston, Canada, p.A3952 ATS 2019 • Dallas, TX 188 MONDAY • MAY 20

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