Browse ATS 2021 Abstracts

HomeProgram ▶ Browse ATS 2021 Abstracts

ATS 2021 will feature presentations of original research from accepted abstracts. Mini Symposia and Thematic Poster Sessions are abstract based sessions.

Please use the form below to browse scientific abstracts and case reports accepted for ATS 2021. Abstracts presented at the ATS 2021 will be published in the Online Abstract Issue of the American Journal of Respiratory and Critical Care Medicine, Volume 203, May 3, 2021.

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Does Vaping Increase the Odds of Asthma?: A Canadian Community Health Survey Study

Session Title
A1645 - Does Vaping Increase the Odds of Asthma?: A Canadian Community Health Survey Study
Author Block: T. To1, K. Zhang1, E. Terebessy1, I. Fong1, J. Zhu1, N. Vozoris2, C. Borkhoff1, T. J. Moraes1, C. Chow3, R. Schwartz4; 1The Hospital for Sick Children, Toronto, ON, Canada, 2St. Michael's Hospital, Toronto, ON, Canada, 3University Health Network, Department of Medicine, University of Toronto, Toronto, ON, Canada, 4University of Toronto, Toronto, ON, Canada.
Rationale: While vaping is thought to be a safer alternative to smoking, emerging research suggests that e-cigarette (EC) use may have long-term health effects and may worsen pre-existing health conditions such as asthma. The objective of this study is to determine whether youth and young adults who are current EC users have increased odds of self-reported asthma and an asthma attack in the last 12 months.
Methods: A cross-sectional study was conducted using the 2015-16 and 2017-18 cycles of the Canadian Community Health Survey (CCHS). The CCHS is a cross-sectional survey that collects self-reported information about health status, health determinants, and behaviours. The study cohort included all Canadians aged 12 years and over who participated in the CCHS. A propensity score method was used to identify five matched controls to individuals with self-reported EC use. Individuals were matched by CCHS cycle, age, sex, province of residence, local health unit, body mass index (BMI), household income, education, mental health, smoking history, and life stress. Odds ratios and 95% confidence intervals (CI) with asthma as the outcome and EC use as the exposure were determined using matched logistic regression, adjusting for potential confounding variables including those used for the propensity score matching. Modelling by smoking subgroup was also conducted.
Results: The study cohort included 17,190 matched individuals from 222,949 CCHS respondents. 16.7% reported EC use in the past 30 days. Univariate analysis found an odds ratio of 1.19 (95% CI: 1.05-1.34) between EC use and self-reported asthma. Adjusting for potential confounders, individuals with EC use had 19% higher odds of having asthma (95% CI: 1.05-1.35). Current and former smokers had 20% (95% CI: 1.02-1.41) and 33% (95% CI: 1.05-1.69) higher odds of having asthma, respectively, while never smokers did not have significant associations, adjusted for potential confounders. Among those with asthma, EC users had 29% (95% CI: 1.02-1.63) higher odds of having an asthma attack in the last 12 months, adjusted for potential confounders.
Conclusions: Current EC use is associated with significantly increased odds of having asthma, that is comparable to current smokers. These findings suggest that EC use is a modifiable risk factor for asthma to be considered in the primary care of youth and young adults.
Figure 1. Adjusted‡ odds ratios of self-reported asthma from matched multivariable logistic regression for selected variables.
‡ Odds ratios adjusted for age, sex, province, BMI, household income, education, mental health, smoking history, and life stress.