ATS 2021 will feature presentations of original research from accepted abstracts. Mini Symposia and Thematic Poster Sessions are abstract based sessions.
Please use the form below to browse scientific abstracts and case reports accepted for ATS 2021. Abstracts presented at the ATS 2021 will be published in the Online Abstract Issue of the American Journal of Respiratory and Critical Care Medicine, Volume 203, May 3, 2021.
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Excess Healthcare Utilization and Mortality in Younger Adults with COPD Compared to Those Without COPD
Session Title
C8 - C008 INNOVATIONS AND UPDATES IN THE STUDY AND MANAGEMENT OF COPD
Abstract
A1131 - Excess Healthcare Utilization and Mortality in Younger Adults with COPD Compared to Those Without COPD
Author Block: A. J. Blazer1, R. McGihon2, A. S. Gershon3; 1Respirology, University of Toronto- Toronto Western Hospital, Toronto, ON, Canada, 2Canadian Institute for Health Information, Toronto, ON, Canada, 3Sunnybrook Health Sciences Centre, Toronto, ON, Canada.
Rationale: Chronic obstructive pulmonary disease (COPD) is a common chronic condition that places a large burden on healthcare systems. Generally considered a disease of older adults, COPD can also affect younger patients, but less attention has been paid to the clinical features of COPD in younger individuals. A common assumption is that COPD diagnosed earlier in life can be equated with a milder severity of disease. However, this has not been fully examined in a real-world population study. The objective of this study was to examine health services utilization and mortality in younger adults with and without COPD. Older adults were also examined as a comparison group.Methods: A longitudinal, population cohort study was conducted using health administrative data from the 14 million diverse residents of Ontario, Canada. All younger adults (35 to 55 years) and older adults (>65 years) with COPD were identified using a validated case definition. Annual mortality and health services use (HSU) rates were calculated between 2006 and 2016 and compared between sexes, across age groups and to corresponding rates from the non-COPD 2016 Ontario population. Results: Younger adults with COPD had significantly increased rates of HSU and mortality compared to the non-COPD population. All-cause emergency department (ED) visits, hospitalizations and all-cause outpatient visits were significantly higher in younger adults with COPD compared to their non-COPD counterparts. Rates of all-cause ED visits and all-cause outpatient visits among younger adults with COPD exceeded rates seen in older adults without COPD. Younger adults with COPD, however, had elevated mortality rate compared to those without COPD (5.6-fold greater rate for females, 4.5-fold greater rate for males), an elevation much more pronounced than in older people.Discussion: Our data demonstrates that younger adults with COPD experience significant morbidity and excessive mortality from their disease. This study provides further evidence that “early” COPD is not a benign entity. Clinical efforts should focus on targeting younger adults with COPD with earlier interventions that can improve their state of health and prevent further progression of their disease.
Author Block: A. J. Blazer1, R. McGihon2, A. S. Gershon3; 1Respirology, University of Toronto- Toronto Western Hospital, Toronto, ON, Canada, 2Canadian Institute for Health Information, Toronto, ON, Canada, 3Sunnybrook Health Sciences Centre, Toronto, ON, Canada.
Rationale: Chronic obstructive pulmonary disease (COPD) is a common chronic condition that places a large burden on healthcare systems. Generally considered a disease of older adults, COPD can also affect younger patients, but less attention has been paid to the clinical features of COPD in younger individuals. A common assumption is that COPD diagnosed earlier in life can be equated with a milder severity of disease. However, this has not been fully examined in a real-world population study. The objective of this study was to examine health services utilization and mortality in younger adults with and without COPD. Older adults were also examined as a comparison group.Methods: A longitudinal, population cohort study was conducted using health administrative data from the 14 million diverse residents of Ontario, Canada. All younger adults (35 to 55 years) and older adults (>65 years) with COPD were identified using a validated case definition. Annual mortality and health services use (HSU) rates were calculated between 2006 and 2016 and compared between sexes, across age groups and to corresponding rates from the non-COPD 2016 Ontario population. Results: Younger adults with COPD had significantly increased rates of HSU and mortality compared to the non-COPD population. All-cause emergency department (ED) visits, hospitalizations and all-cause outpatient visits were significantly higher in younger adults with COPD compared to their non-COPD counterparts. Rates of all-cause ED visits and all-cause outpatient visits among younger adults with COPD exceeded rates seen in older adults without COPD. Younger adults with COPD, however, had elevated mortality rate compared to those without COPD (5.6-fold greater rate for females, 4.5-fold greater rate for males), an elevation much more pronounced than in older people.Discussion: Our data demonstrates that younger adults with COPD experience significant morbidity and excessive mortality from their disease. This study provides further evidence that “early” COPD is not a benign entity. Clinical efforts should focus on targeting younger adults with COPD with earlier interventions that can improve their state of health and prevent further progression of their disease.
